Kinneretia THG-SQI4 mediated biosynthesis of silver nanoparticles and its antimicrobial efficacy.

Kinneretia THG-SQI4 mediated biosynthesis of silver nanoparticles and its antimicrobial efficacy.

Artif Cells Nanomed Biotechnol. 2017 May;45(3):602-608

Authors: Singh H, Du J, Yi TH

Abstract
Simple, facile, effective approach for the biosynthesis of silver nanoparticles using Kinneretia species and its antimicrobial activity against human pathogens has been demonstrated in this study. Kinneretia THG-SQI4 has been isolated from soil sample collected from Shangqui, China. The synthesized nanoparticles were characterized by ultraviolet-visible spectrophotometry (UV-vis), field emission transmission electron microscopy (FE-TEM), energy dispersive X-ray spectroscopy (EDX), elemental mapping, selected area diffraction pattern, and X-ray diffraction (XRD). The synthesized silver nanoparticles were characterized by a peak at 425 nm in the UV-vis spectrum. The TEM data reveals that the nanoparticles are monodisperse and spherical in shape having a diameter ranging from 15 to 20 nm. The bright circular spots in SAED pattern confirm the crystalline nature of the nanoparticles. The XRD spectra exhibited the characteristic Bragg peaks of 1 1 1, 2 0 0, 2 2 0, and 3 1 1 facets of the face centered cubic symmetry of nanoparticles. The synthesized silver nanoparticles showed potent antibacterial activity against human pathogens like Candida albicans, Candida tropicalis, Bacillus cereus, Bacillus subtilis, Staphylococcus aureus, Salmonella enterica, Pseudomonas aeruginosa, Escherichia coli, and Vibrio parahaemolyticus. Moreover, the silver nanoparticles show enhanced synergistic effects in combination with different standard antibiotics against Gram-negative bacteria. This method for synthesis of silver nanoparticle is valuable and has antimicrobial potential.

PMID: 28211298 [PubMed - in process]

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