MRI findings of optic pathway involvement in Miller Fisher syndrome in 3 pediatric patients and a review of the literature.

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MRI findings of optic pathway involvement in Miller Fisher syndrome in 3 pediatric patients and a review of the literature.

J Clin Neurosci. 2017 Feb 10;:

Authors: Malhotra A, Zhang M, Wu X, Jindal S, Durand D, Makhani N

Abstract
BACKGROUND: Miller Fisher syndrome (MFS) is a rare demyelinating condition which may have involvement of cranial nerves. There are a few case reports of optic pathway involvement in children. We describe 3 patients with optic pathway enhancement in pediatric patients with MFS.
CASE SERIES: We retrospectively reviewed brain imaging findings in 17 pediatric patients with of Guillain-Barré syndrome (GBS) meeting Brighton criteria who had brain MRIs performed during their acute illness. Cranial nerve enhancement was seen in 6/17 patients and optic nerve/chiasm enhancement was seen in 3 patients.
CONCLUSION: Cranial nerve enhancement and optic pathway in particular, can be seen in patients with MFS. Imaging findings do not always correlate with clinical manifestations of cranial nerve involvement.

PMID: 28209311 [PubMed - as supplied by publisher]

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