Publication date: Available online 1 February 2017
Source:Microbes and Infection
Author(s): Etienne Ruppé, Gilbert Greub, Jacques Schrenzel
Metagenomics is recently entering in the clinical microbiology and an increasing number of diagnostic laboratories are now proposing the sequencing & annotation of bacterial genomes and/or the analysis of clinical samples by direct or PCR-based metagenomics with short time to results. In this context, the first International Conference on Clinical Metagenomics (ICCMg) was held in Geneva in October 2016 and several key aspects have been discussed including: (i) the need for improved resolution, (ii) the importance of interpretation given the common occurrence of sequence contaminants, iii) the need for improved bioinformatic pipelines, iv) the bottleneck of DNA extraction, v) the importance of gold standards, vi) the need to further reduce time to results, vii) how to improve data sharing, viii) the applications of bacterial genomics and clinical metagenomics in better adapting therapeutics and ix) the impact of metagenomics and new sequencing technologies in discovering new microbes. Further efforts in term of reduced turnaround time, improved quality and lower costs are however warranted to fully translate metagenomics in clinical applications.
http://ift.tt/2jF13TH
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00302841026182
00306932607174
alsfakia@gmail.com
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- The efficacy study of the combination of tripeptid...
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- Characterizing the detectability of emission signa...
- Public member dose assessment of Bushehr Nuclear P...
- Radioactivity levels in the mostly local foodstuff...
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- Primary Thyroid Carcinoma with Low-Risk Histology ...
- Effects of Adequate Iodine Supply on the Incidence...
- Acknowledgment of Reviewers
- Shigenobu Nagataki (January 18, 1932–November 12, ...
- Future Meetings
- Primary Thyroid Carcinoma with Low-Risk Histology ...
- Effects of Adequate Iodine Supply on the Incidence...
- Acknowledgment of Reviewers
- Shigenobu Nagataki (January 18, 1932–November 12, ...
- Future Meetings
- Blockage of androgen and administration of estroge...
- Quantifying 125I placement accuracy in prostate br...
- MRI in prostate brachytherapy: Evidence, clinical ...
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- Survival, Morbidity, and Quality-of-Life Outcomes ...
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