Statistical Concerns on Vismodegib for Basal Cell Carcinoma Meta-Analysis

To the Editor The recent meta-analysis published by Jacobsen and colleagues in JAMA Dermatology amalgamated all available evidence pertaining the role of vismodegib for locally advanced and metastatic basal cell carcinoma. Well-conducted meta-analyses can provide more accurate estimates of response and safety and investigate further the reasons for clinical discrepancies across studies.

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