Beyond Digestion: The Pancreas Shapes Intestinal Microbiota and Immunity

Publication date: 7 March 2017
Source:Cell Metabolism, Volume 25, Issue 3
Author(s): Herbert Tilg, Timon E. Adolph
Our understanding of the regulatory mechanisms that shape the gut microbiota is rapidly emerging. The intestinal microbial landscape is modulated by a plethora of host-extrinsic and host-intrinsic factors. In this issue of Cell Metabolism, Ahuja and colleagues (2017) demonstrate that mediators secreted by pancreatic acini shape the intestinal microbiota and intestinal immunity.

Teaser

Our understanding of the regulatory mechanisms that shape the gut microbiota is rapidly emerging. The intestinal microbial landscape is modulated by a plethora of host-extrinsic and host-intrinsic factors. In this issue of Cell Metabolism, Ahuja and colleagues demonstrate that mediators secreted by pancreatic acini shape the intestinal microbiota and intestinal immunity.


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