Delivery of glycerol trinitrate after reconstruction with an oral free flap

We write to highlight an important clinical point that we recently encountered in a patient who had been treated by resection of the floor of the mouth. His past medical history included ischaemic heart disease and he was admitted for operation with an already prescribed glycerol trinitrate spray "as required" for his cardiac problems. Although there are many different ways to deliver the drug, a spray on to the sublingual mucosa provides the fastest response.

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