Calculating the Tumor Volumes in Vestibular Schwannomas: Are the ABC/2 and Volumetric Methods Comparable?

Calculating the Tumor Volumes in Vestibular Schwannomas: Are the ABC/2 and Volumetric Methods Comparable?

Otol Neurotol. 2017 Apr 07;:

Authors: Bathla G, Policeni B, Hansen MR, Berbaum K

Abstract
PURPOSE: To assess the efficacy of the ABC/2 method for calculating the volume of vestibular schwannomas as compared with 3-D planimetric method.
STUDY DESIGN: Retrospective.
METHODS: Fifty eight cases of pathologically confirmed sporadic vestibular schwannomas (VS) were analyzed. Tumors volumes were calculated for each tumor twice, once through semiautomated 3-D volumetric method and subsequently through ABC/2 (AP × ML × CC/2) methodology after calculating the maximal tumor dimensions in anteroposterior (AP), coronal (ML), and craniocaudal (CC) dimensions. Tumor volumes were initially correlated as a group and subsequently by dividing them into three groups using the Hannover classification.
RESULTS: The two methodologies were highly correlated when tumors were analyzed as a group (rho = 0.913, p < 0.0001). In the sub-group analysis, tumor volumes were again strongly correlated for larger tumors (rho = 0.918, p < 0.0001) but the correlation progressively reduced as tumor volumes decreased.
CONCLUSION: Given the ease and universal accessibility of linear measurement applications, the ABC/2 methodology is a robust substitute for calculating tumor volumes, especially for larger tumors.

PMID: 28394785 [PubMed - as supplied by publisher]

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