Background: Melanoma is a rare neoplasm in the pediatric population. Recent publications suggest a possible increase in incidence over the past few decades. The purpose of this study was to analyze trends in pediatric patients diagnosed with malignant melanoma in British Columbia (BC) in the past 35 years. Methods: A retrospective review was performed. All patients in BC diagnosed with melanoma before 18 years of age from 1979 to 2014 were included. Patient demographics, melanoma description, treatment details, and survival data were collected. Results: Seventy-eight subjects were identified for the study. Patients were equally distributed by sex. Sixty-one (78%) of the subjects were diagnosed in the postpubertal age (≥12 years old). The most common sites of occurrence were the extremities (n = 33) and the trunk (n = 27), with the location on the trunk showing the highest mortality rate (22%). All patients were surgically treated and some had additional chemotherapy (12) and/or radiotherapy (12). Fatal outcome was recorded in 12 of the 78 subjects, 10 of whom had postpubertal diagnosis. The average time from date of diagnosis to date of death was 9.3 years. Conclusions: The incidence of melanoma in the pediatric population remains exceedingly rare: less than 2.5 per million children younger than 18 years. The diagnosis is rarely made before puberty; the incidence is equal in males and females and has not changed over a 35-year time period in BC. Our study shows 85% survival with the majority of patients having had surgical excision only.
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Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com
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- Anisotropic tough double network hydrogel from fis...
- Activatable near infrared dye conjugated hyaluroni...
- Peptide valency plays an important role in the act...
- Determination of forces on a split palatal screw a...
- International Journal of Otolaryngology and Head &...
- International Journal of Otolaryngology and Head &...
- Prophylactic atropine administration attenuates th...
- Effects of different fresh gas flows with or witho...
- Prophylactic atropine administration attenuates th...
- Effects of different fresh gas flows with or witho...
- Differential Regulation of chTLR3 by Infectious Bu...
- The epigenetic mechanism for discordance of autoim...
- Antimicrobial and anti-inflammatory activities, wo...
- Paeoniflorin and liquiritin, two major constituent...
- Effects of Gnaphalium affine D. Don on hyperuricem...
- An overview on Leucosidea sericea Eckl. & Zeyh.: A...
- The senile functional evolution of the larynx afte...
- "Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"[jo...
- Food labeling issues in patients with severe food ...
- Drug use among transgender people in Ontario, Cana...
- Variation of Housekeeping Genes in Clinical Isolat...
- Enforced miR-144-3p Expression as a Non-Invasive B...
- Matrix-Assisted Laser Desorption-Ionization Time-o...
- Association of Serum Interleukin-28B with Clinical...
- Efficiency of Leukocyte Differential Using Flow Cy...
- Genetic Polymorphism of Epidermal Growth Factor rs...
- Diagnosis of Hepatitis C Virus Infection Using a N...
- Genetic Polymorphism of MTHFR C677T Influences Sus...
- Estimation of Diagnostic Markers in Rheumatoid Art...
- Point of Care Cardiac Troponin Assay Analytical Pe...
- Real-time PCR Detection of the Most Common Bacteri...
- Evaluation of MALDI-TOF-MS for the Identification ...
- Evaluation of the Three Customized MSI Panels to I...
- Factors Contributing to False-Negative Enzyme-Link...
- Comparison of Novel Blood Culture System DL-Bt112T...
- Interactions of Methylenetetrahydrofolate Reductas...
- Intracellular Storage of Duffy Antigen-Binding Che...
- Increase of C3a is Associated with Hemorrhagic Pro...
- Absolute Eosinophil Count was Significantly Associ...
- Effects of Ulinastatin on In Vitro Storage Lesions...
- Food labeling issues in patients with severe food ...
- Food labeling issues in patients with severe food ...
- Role of Postoperative Stimulated Thyroglobulin as ...
- Clear Cell Change in Thyroid Carcinoma: A Clinicop...
- Task-optimal auditory attention set restored as fa...
- Role of Postoperative Stimulated Thyroglobulin as ...
- Clear Cell Change in Thyroid Carcinoma: A Clinicop...
- Exposure to Extrinsic Stressors, Social Defeat or ...
- Coexpressed modular gene expression reveals invers...
- Molecular imprinting sensor based on quantum weak ...
- Dialysis membrane-enforced microelectrode array me...
- One-pot loading high-content thionine on polydopam...
- InGaN/GaN nanowires as a new platform for photoele...
- Prognostic implication of CD274 (PD-L1) protein ex...
- A dynamic sandwich assay on magnetic beads for sel...
- Immunodetection of salivary biomarkers by an optic...
- Bipolar electrochemiluminescence on thread: A new ...
- Aluminium resistant, plant growth-promoting bacter...
- Nutrition modulation of human aging: The calorie r...
- Vitamin D signaling in intestinal innate immunity ...
- Small non coding RNAs in adipocyte biology and obe...
- News and Announcements
- Chromium concentrations in ruminant feed ingredients
- Enteric methane production in lactating dairy cows...
- Invited review: Determinants of farmers' adoption ...
- Invited review: Anti-adhesive properties of bovine...
- Interpretive Summaries, May 2017
- Characterization of major and trace minerals, fatt...
- Benchmarking passive transfer of immunity and grow...
- Evaluating a commercial PCR assay against bacteria...
- Prevalence, antimicrobial resistance, and molecula...
- Antibiotic treatment of metritis in dairy cows—A m...
- Application of a bacteriological on-farm test to r...
- Application of gene detection technique in the ant...
- Application of gene detection technique in the ant...
- The Role of Plastic Surgery at an Academic Medical...
- Quantitative Measurements of the Bulbous Tip in Et...
- Application for MEDPOR Surgical Implant in Modifie...
- Lateral Thoracodorsal Flap or Lateral Intercostal ...
- Book Review: A Practical Guide on Operative Techni...
- Using Levator Aponeurosis to Create Physiologicall...
- Rigid Sternal Fixation Versus Modified Wire Techni...
- Utilization and Perception of Integrative Medicine...
- Postsurgical Pyoderma Gangrenosum Versus Necrotizi...
- Management of Gynecomastia in Patients With Differ...
- Classification and Application of the Distally-Bas...
- The Gaza Hand Board
- Lars Vistnes, MD, 1927–2016
- Modified Functional Superficial Parotidectomy With...
- The Combined Use of a Neurocutaneous Flap and the ...
- Internal Distraction Osteogenesis With Piezosurger...
- The Teaching of Ethics and Professionalism in Plas...
- Deep Inferior Epigastric Perforator Versus Free Tr...
- Improved Survival of Full-Thickness Skin Graft Wit...
- Women’s Experiences With Flap Failure After Autolo...
- Kinetics of lipid bilayer permeation of a series o...
- Innovative approach for identifying root causes of...
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