Classification of Meningiomas Based on their Surgical Removal, Who Grade, and Cytogenetic Profile: A Treatment Algorithm.

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Classification of Meningiomas Based on their Surgical Removal, Who Grade, and Cytogenetic Profile: A Treatment Algorithm.

World Neurosurg. 2017 Jun 03;:

Authors: Eduardo da Silva C, Peixoto de Freitas PE

Abstract
BACKGROUND: Meningiomas are the most common primary intracranial tumor but the lack of prospective randomized trials has led to different guidelines for their treatment. In this paper, we propose a classification of meningiomas that considers, surgical removal, histology and cytogenetic profile, this based on a literature review of these three criteria. The classification can be used to guide adjuvant treatment and follow-up.
METHODS: Retrospective PubMed literature review from 2007 to 2016. The search terms were: meningiomas, surgery, WHO classification, cytogenetic, and algorithm.
RESULTS: Meningiomas were classified into five groups (A-E) according to the Simpson resection grade, World Health Organization grade, and cytogenetic profile. Adjuvant therapy, follow-up magnetic resonance imaging, and recurrence/regrowth management were proposed according to the classification.
CONCLUSIONS: The proposed meningioma classification is based on our experience and retrospective evidence collated from literature and supported by recommendations. The application of the classification criteria yielded an algorithm for the treatment and follow-up of meningioma patients.

PMID: 28587980 [PubMed - as supplied by publisher]

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