The role of environmental exposure to peanut in the development of clinical allergy to peanut

Abstract

The presence of peanut allergy has increased over the years and still remains one of the most common causes of food-related anaphylaxis. The way in which peanut sensitization occurs has been explored, such as via maternal consumption in pregnancy, via breast milk and through a disrupted skin barrier. It has previously been shown that environmental exposure to aeroallergens in household dust can be a risk factor for the development of allergic asthma. However, it is likely that the combination of cutaneous sensitisation via a disrupted skin barrier (i.e. children with eczema especially those with filaggrin mutations) and the interaction with environmental peanut exposure influences the development of peanut allergy. This review aims to explore the current evidence of how environmental exposure to peanut affects the development of peanut allergy.

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