Chemotherapy in head and neck osteosarcoma: Adjuvant chemotherapy improves overall survival

Osteosarcoma is a common bone malignancy characterized by osteoid formation by highly malignant osteoblasts [1], osteosarcoma occurs commonly in the extremity of children and adolescents and rarely in the head and neck sites, only 6% to 10% of all osteosarcomas are reported to occur in head and neck sites [2,3]. The tumor is aggressive and often presents with high histological grade [4] and propensity towards lung metastasis [5]. Surgery is the main therapeutic modality for cure. However; many trials indicate the benefit of adjuvant chemotherapy in improving survival of these patients [6].

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