Demographic and clinicopathological characteristics of nasopharyngeal carcinoma and survival outcomes according to age at diagnosis: A population-based analysis

Though rare in Japan and western countries, nasopharyngeal carcinoma (NPC) is endemic in southern China, Southeast Asia and Southern Africa. In general, the incidence of NPC in endemic and non-endemic areas has stabilised in recent decades [1,2]; however, the age distribution varies between endemic and non-endemic areas. The age distribution of NPC is unimodal in endemic areas, peaking in individuals aged 45–59-years-old [1,2]. However, in low risk populations, the age distribution is bimodal, with a first peak in young adolescents (aged 15–19) and a second peak in individuals aged 65–79 [1].

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