Cosmetics, Vol. 4, Pages 47: New Method of Measurement of Epidermal Turnover in Humans

Cosmetics, Vol. 4, Pages 47: New Method of Measurement of Epidermal Turnover in Humans

Cosmetics doi: 10.3390/cosmetics4040047

Authors: Kazuhisa Maeda

This report describes a new and simple technique to detect alterations in the rate of turnover in the epidermis without using any toxic chemical, such as a radiolabeled material. The method involves measuring the time course of the decrease of darkening of an ultraviolet A-irradiated site, compared with a non-irradiated control site. The turnover time of the persistent pigmentation on the inner side of the male forearm was 36.2 ± 6.2 days (age: 37.3 ± 11.3 years, mean ± standard deviation, n = 6), which is in reasonable agreement with the epidermal turnover time previously measured by injecting [3H] thymidine into human skin.

http://ift.tt/2jfj4xJ