Marjolin's ulcer in a 20 years old split thickness skin graft on the knee-A case report.

Marjolin's ulcer in a 20 years old split thickness skin graft on the knee-A case report.

Int J Surg Case Rep. 2017 Dec 05;42:102-103

Authors: Saltvig I, Matzen SH

Abstract
OBJECTIVE: Marjolin's Ulcer (MU) is a rare cutaneous neoplasm arising in cikatrical tissue. Due to its typical clinical presentation as a non-healing lesion in scar tissue, the diagnosis can be delayed and even overlooked.
METHODS AND RESULTS: We present the case of an elderly woman who developed an ulcerated, exophytic lesion in a split thickness skin graft (STSG) on the lateral aspect of the left knee. Histology showed a radically excised highly differentiated squamous cell carcinoma (SCC) with keratine pearls and a component of basocellular carcinoma (BCC). The histological picture combined with the location and long time interval since the primary surgery made the diagnosis of MU highly likely.
DISCUSSION: Considering the risk of metastasis and mortality it is important to recognize the diagnosis and initiate adequate treatment.
CONCLUSION: The diagnosis of MU is clinical and confirmed by pathology. The typical long delay from the primary lesion to the malignant transformation might occlude the diagnosis. As such, a thorough anamnesis is essential in a non- healing ulcerated lesion in a cikatrical area to adequately diagnose and treat the condition.

PMID: 29241101 [PubMed - as supplied by publisher]

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