Adverse drug event following self-medication among ambulatory care patients in a tertiary Hospital in Ebonyi State

Chihurumnanya Alo, Nneamaka Chikerenma Alo, Nnaemeka C Oguejiofor, Ifeyinwa Chizoba Akamike

African Journal of Medical and Health Sciences 2017 16(2):99-103

Background: An adverse drug event (ADE) is defined as any injury, including physical harm, mental harm, or loss of function due to medication. Little is known about ADEs in ambulatory care settings. Self-medication by definition is the practice of taking medicines by individuals to treat self-recognized symptoms or illness. Aim: The objective of this study was to find out the prevalence of ADEs that occurred as a result of self-medication among ambulatory care patients in our center. Methodology: A cross-sectional study where a paper-based, pretested, semi-structured interviewer administered questionnaire was used to gather information from 398 adult patients attending the general outpatient clinic of a tertiary hospital. Data analysis was performed using Epi Info 7 and all statistical significance was set at P < 0.05. Results: The study had 398 respondents of which 161 (40.45%) and 237 (59.55%) were males and females, respectively. Mean age and the standard deviation was 37.17 ± 14.91. The frequency of self-medication was 375 (89.7%) and the frequency of those who have had at least one episode of ADE following self-medication was 88 (22.11%). Females, (207) significantly practiced self-medication than males (150), Z = 4.19, confidence interval (8.45, 23.49), P = 0.00002. ADE following self-medication occurred more in females (50) than in males, (38) and was not associated with self-medication. The majority of the symptoms reported were itching (47.73%), blurring of vision (14.77%), and abdominal pain. Conclusion: ADEs happen following self-medication among ambulatory patients, especially in women and among the married.

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