Data on differentially expressed miRNAs in dogs infected with Leishmania infantum

Publication date: April 2018
Source:Data in Brief, Volume 17
Author(s): Jaqueline Poleto Bragato, Larissa Martins Melo, Gabriela Lovizutto Venturin, Gabriela Torres Rebech, Leandro Encarnação Garcia, Flavia Lombardi Lopes, Valéria Marçal Felix de Lima
This paper contains data on differentially expressed miRNAs in peripheral blood mononuclear cells (PBMC) of dogs naturally infected by Leishmania (L.) infantum compared to healthy dogs. In recent years, studies with miRNAs have shown that these molecules play a critical role in the regulation and function of immune response.Differentially expressed miRNAs were identified by microarray, validated by real time PCR and compared with parasite load in the dogs. Targets and pathways were analyzed using the Ingenuity Pathway Analysis program.



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