Concomitant cutaneous squamous cell carcinoma and CLL in a patient: The utility of 18 F- FDG PET/CT in differentiation of nodal metastasis.

Concomitant cutaneous squamous cell carcinoma and CLL in a patient: The utility of 18 F- FDG PET/CT in differentiation of nodal metastasis.

Am J Hematol. 2018 Jan 17;:

Authors: Ozturk K, Ustun C, Khaja S, Li F, Rischall M, Cayci Z

Abstract
INTRODUCTION: Head and neck cutaneous squamous cell carcinoma (cSCC) often presents with cervical lymph node metastases. Lymphoma is the second most common malignancy in the cervical region, however, it is rarely synchronous with head and neck cSCC.
METHODS: We describe the unusual presentation of a patient with small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL) and metastatic head and neck cSCC on 18-fluorodeoxyglucose positron emission tomography (18 F-FDG PET/CT).
RESULTS: In our case, 18 F-FDG PET/CT was able to detect single sub-centimeter SCC metastatic node among numerous other enlarged CLL infiltrated lymph nodes since SCC was markedly more FDG avid comparison with CLL lymph nodes. This single highly FDG avid node was otherwise occult by clinical examination and indifferent from the rest of the lymph nodes on routine cross-sectional imaging.
CONCLUSION: This report describes the role of 18 F-FDG PET/CT in differentiation of the single sub-centimeter metastatic nodal disease from cSCC from the remainder innumerable leukemia infiltrated nodes. This article is protected by copyright. All rights reserved.

PMID: 29341235 [PubMed - as supplied by publisher]

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