Source:Magnetic Resonance Imaging, Volume 48
Author(s): Kazuya Yasokawa, Katsuyoshi Ito, Akihiko Kanki, Akira Yamamoto, Teruyuki Torigoe, Tomohiro Sato, Tsutomu Tamada
PurposeTo evaluate the correlation between the pancreatic exocrine insufficiency estimated by cine-dynamic MRCP using spatially selective IR pulse and the severity stages (modified Cambridge classification) based on morphological changes of the pancreatic duct in patients with suspected chronic pancreatitis.Materials and methodsThirty-nine patients with suspected chronic pancreatitis underwent cine-dynamic MRCP with a spatially selective IR pulse. The secretion grading score (5-point scale) based on the moving distance of pancreatic juice inflow on cine-dynamic MRCP was assessed, and compared with the stage of the severity of chronic pancreatitis based on morphological changes of pancreatic duct.ResultThe stage of the severity of chronic pancreatitis based on morphological changes had significant negative correlations with the secretion grade (r=−0.698, P<0.001). The secretion grading score of stage 4 was significantly lower than stage 1–3 (P<0.001, P=0.002, P=0.025, respectively). In all 19 patients in stage 4, the secretion grading score was <0.70. The secretion grading score of stage 1 was significantly higher than stage 2 and 4 (P=0.019, P<0.001, respectively). In stage 2, the secretion grading score was <0.70 in 8 (89%) of 9 patients showing pancreatic exocrine insufficiency. Conversely, in stage 3, the secretion grading score was >0.70 in 2 (33%) of 6 patients showing normal pancreatic exocrine function.ConclusionIt should be noted that the degree of morphological changes of pancreatic duct does not necessarily reflect the severity of pancreatic exocrine insufficiency at cine-dynamic MRCP in stage 2–3 chronic pancreatitis.
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