OBJECTIVES: To assess the impact of vasopressin on the microcirculation and to develop a predictive model to estimate the probability of microcirculatory recruitment in patients with septic shock. METHODS: This prospective interventional study included patients with septic shock receiving noradrenaline for less than 48 hours. We infused vasopressin at 0.04 U/min for one hour. Hemodynamic measurements, including sidestream dark-field imaging, were obtained immediately before vasopressin infusion, 1 hour after vasopressin infusion and 1 hour after vasopressin withdrawal. We defined patients with more than a 10% increase in total vascular density and perfused vascular density as responders. ClinicalTrials.gov: NCT02053675. RESULTS: Eighteen patients were included, and nine (50%) showed improved microcirculation after infusion of vasopressin. The noradrenaline dose was significantly reduced after vasopressin (p=0.001) and was higher both at baseline and during vasopressin infusion in the responders than in the non-responders. The strongest predictor for a favorable microcirculatory response was the dose of noradrenaline at baseline (OR=4.5; 95% CI: 1.2-17.0; p=0.027). For patients using a noradrenaline dose higher than 0.38 mcg/kg/min, the probability that microcirculatory perfusion would be improved with vasopressin was 53% (sensitivity 78%, specificity 77%). CONCLUSIONS: In patients with septic shock for no longer than 48 h, administration of vasopressin is likely to result in an improvement in microcirculation when the baseline noradrenaline dose is higher than 0.38 mcg/kg/min.
http://ift.tt/2CRY2xX
Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com
Αρχειοθήκη ιστολογίου
-
►
2023
(391)
- ► Φεβρουαρίου (200)
- ► Ιανουαρίου (191)
-
►
2022
(2843)
- ► Δεκεμβρίου (161)
- ► Σεπτεμβρίου (219)
- ► Φεβρουαρίου (264)
- ► Ιανουαρίου (280)
-
►
2021
(5625)
- ► Δεκεμβρίου (231)
- ► Σεπτεμβρίου (345)
- ► Φεβρουαρίου (620)
-
►
2020
(2065)
- ► Δεκεμβρίου (535)
- ► Σεπτεμβρίου (222)
- ► Φεβρουαρίου (28)
-
►
2019
(9608)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (3791)
- ► Ιανουαρίου (3737)
-
▼
2018
(69720)
- ► Δεκεμβρίου (3507)
- ► Σεπτεμβρίου (3851)
- ► Φεβρουαρίου (8116)
-
▼
Ιανουαρίου
(7758)
-
▼
Ιαν 08
(279)
- Exploratory study of atmospheric methane enhanceme...
- Detection of nuclear testing from surface concentr...
- Removal of lead and cadmium from aqueous solutions...
- Is insufficient pulmonary air support the cause of...
- BRCA1 mutation spectrum, functions and therapeutic...
- Adipocytokines and Breast Cancer
- Drug Development and Clinical Trial Design in Panc...
- Primary Hepatic Marginal zone Lymphoma: A rare coi...
- Exogenous Cushing syndrome due to misuse of potent...
- Doing the math: A simple approach to topical timol...
- Mood changes with methotrexate therapy for dermato...
- Pityriasis lichenoides: Long-term follow-up study
- Incidence, outcomes, and resource use in children ...
- Towards an international language for Incontinence...
- Towards an international language for Incontinence...
- Risk Factors Affecting the Prognosis of Descending...
- Linear and cyclic amylose derivatives having brush...
- Largely improved mechanical properties of a biodeg...
- Imatinib-induced pseudoporphyria
- Imatinib-induced pseudoporphyria
- The effect of single and repeated prefrontal inter...
- Effects of TDCS dosage on working memory in health...
- Size-based separation methods of circulating tumor...
- Molecular analysis of circulating tumors cells: Bi...
- Movement-related neural processing in people with ...
- The cortical focus in childhood absence epilepsy; ...
- Ischemic Stroke Mandates Cross-Disciplinary Collab...
- Prevention of "Failure": Is It a Failure of Preven...
- Potential US Population Impact of the 2017 ACC/AHA...
- Empagliflozin and Clinical Outcomes in Patients Wi...
- Sodium/Glucose Cotransporter 2 Inhibitors in Patie...
- Influence of Baseline Diastolic Blood Pressure on ...
- Benefits and Risks of Antihypertensive Treatment: ...
- Exercise Intolerance in Heart Failure With Preserv...
- Can Oxygen Transport Analysis Tell Us Why People W...
- Extracellular Matrix Proteomics Reveals Interplay ...
- Early Detection of Subclinical Myocardial Damage i...
- High Costs and Caution Yield Slow Start for New He...
- Bayes Syndrome: What Is It?.
- Accelerometer-Measured Physical Activity and Seden...
- Risks of Overinterpreting Interim Data: Lessons Fr...
- Letter by Chen and Shen Regarding Article, "Exosom...
- Response by Marban and de Couto to Letter Regardin...
- Letter by Ianiro et al Regarding Article, "Effect ...
- Letter by Jin-shan and Xue-bin Regarding Article, ...
- Quantitative Analysis Of Lipid Debris Accumulation...
- The effects of melatonin and curcumin on the expre...
- Viable tumor in salvage neck dissections in head a...
- Management of treatment failure in restless legs s...
- Long-term outcomes after percutaneous renal cryoab...
- Sustained improvement of psoriasis associated with...
- Double-balloon enteroscopy (DBE) in patients prese...
- A difficult diagnosis of coeliac disease: Repeat d...
- Inflammation induced ER stress affects absorptive ...
- Quantitative CT Assessment of Gynecomastia in the ...
- Tracking diet variety in childhood and its associa...
- Parental feeding practices to manage snack food in...
- An RNA-seq screen of P. gingivalis LPS treated hum...
- Ultrastructural damage in Streptococcus mutans inc...
- SUPRAGINGIVAL AND SUBGINGIVAL MICROBIOTA FROM PATI...
- BET’ing on Dual JAK/BET Inhibition as a Therapeuti...
- Characterizing the Killer Colorectal Carcinomas
- A TFIID-SAGA Perturbation that Targets MYB and Sup...
- TIM-3 Regulates CD103+ Dendritic Cell Function and...
- Oncogenic KRAS Regulates Amino Acid Homeostasis an...
- Hedgehog Pathway Drives Fusion-Negative Rhabdomyos...
- Clinical Sequencing Defines the Genomic Landscape ...
- Integrative Analysis Identifies Four Molecular and...
- Arid1a Has Context-Dependent Oncogenic and Tumor S...
- Tumor Evolution of Glioma-Intrinsic Gene Expressio...
- 11q23 deletion syndrome (Jacobsen syndrome) with s...
- Anesthesia for Same Day Discharge After Craniotomy...
- Innate Sex Bias of Staphylococcus aureus Skin Infe...
- Ca2+-Dependent Regulation of NFATc1 via KCa3.1 in ...
- Cytoplasmic Linker Protein CLIP170 Negatively Regu...
- Foxp1 Negatively Regulates T Follicular Helper Cel...
- Osteoblasts Are Rapidly Ablated by Virus-Induced S...
- Time-Restricted Feeding Alters the Innate Immune R...
- mPGES1-Dependent Prostaglandin E2 (PGE2) Controls ...
- In This Issue [IN THIS ISSUE]
- Naive CD4+ T Cells Carrying a TLR2 Agonist Overcom...
- Inhibitors of the PD-1 Pathway in Tumor Therapy [T...
- Role of CD44 in Regulating TLR2 Activation of Huma...
- A Believers Overview of Cancer Immunosurveillance ...
- Metformin Mediates Protection against Legionella P...
- Hitting the Target: How T Cells Detect and Elimina...
- A Role of NKR-P1A (CD161) and Lectin-like Transcri...
- Tissue-Resident Cytolytic Innate Lymphocytes in Ca...
- Early Inhibition of Fatty Acid Synthesis Reduces G...
- Alternative Splicing Transcripts of Zebrafish LGP2...
- Immune Cell Infiltration and Tertiary Lymphoid Str...
- Dendritic Cell RIPK1 Maintains Immune Homeostasis ...
- Dendritic Cell-Based Cancer Vaccines [BRIEF REVIEWS]
- Ex-situ Organ Preservation: The Temperature Paradigm
- Liver Simulated Allocation Modeling: Were the Pred...
- The Effects of Short-Term Subnormothermic Perfusio...
- Antioxidant activity of CAPE (caffeic acid pheneth...
- Benign prostatic hyperplasia surgical scoring (BPH...
- Revision Sinus Surgery Sets the Stage for a Succes...
- Under Pressure: On Call During Hurricane Harvey
-
▼
Ιαν 08
(279)
-
►
2017
(111579)
- ► Δεκεμβρίου (7718)
- ► Σεπτεμβρίου (7549)
- ► Φεβρουαρίου (10753)
- ► Ιανουαρίου (10529)
-
►
2016
(16402)
- ► Δεκεμβρίου (7478)
- ► Φεβρουαρίου (900)
- ► Ιανουαρίου (1250)
! # Ola via Alexandros G.Sfakianakis on Inoreader
Η λίστα ιστολογίων μου
Δευτέρα 8 Ιανουαρίου 2018
Microcirculation improvement after short-term infusion of vasopressin in septic shock is dependent on noradrenaline
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Αρχειοθήκη ιστολογίου
-
►
2023
(391)
- ► Φεβρουαρίου (200)
- ► Ιανουαρίου (191)
-
►
2022
(2843)
- ► Δεκεμβρίου (161)
- ► Σεπτεμβρίου (219)
- ► Φεβρουαρίου (264)
- ► Ιανουαρίου (280)
-
►
2021
(5625)
- ► Δεκεμβρίου (231)
- ► Σεπτεμβρίου (345)
- ► Φεβρουαρίου (620)
-
►
2020
(2065)
- ► Δεκεμβρίου (535)
- ► Σεπτεμβρίου (222)
- ► Φεβρουαρίου (28)
-
►
2019
(9608)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (3791)
- ► Ιανουαρίου (3737)
-
▼
2018
(69720)
- ► Δεκεμβρίου (3507)
- ► Σεπτεμβρίου (3851)
- ► Φεβρουαρίου (8116)
-
▼
Ιανουαρίου
(7758)
-
▼
Ιαν 08
(279)
- Exploratory study of atmospheric methane enhanceme...
- Detection of nuclear testing from surface concentr...
- Removal of lead and cadmium from aqueous solutions...
- Is insufficient pulmonary air support the cause of...
- BRCA1 mutation spectrum, functions and therapeutic...
- Adipocytokines and Breast Cancer
- Drug Development and Clinical Trial Design in Panc...
- Primary Hepatic Marginal zone Lymphoma: A rare coi...
- Exogenous Cushing syndrome due to misuse of potent...
- Doing the math: A simple approach to topical timol...
- Mood changes with methotrexate therapy for dermato...
- Pityriasis lichenoides: Long-term follow-up study
- Incidence, outcomes, and resource use in children ...
- Towards an international language for Incontinence...
- Towards an international language for Incontinence...
- Risk Factors Affecting the Prognosis of Descending...
- Linear and cyclic amylose derivatives having brush...
- Largely improved mechanical properties of a biodeg...
- Imatinib-induced pseudoporphyria
- Imatinib-induced pseudoporphyria
- The effect of single and repeated prefrontal inter...
- Effects of TDCS dosage on working memory in health...
- Size-based separation methods of circulating tumor...
- Molecular analysis of circulating tumors cells: Bi...
- Movement-related neural processing in people with ...
- The cortical focus in childhood absence epilepsy; ...
- Ischemic Stroke Mandates Cross-Disciplinary Collab...
- Prevention of "Failure": Is It a Failure of Preven...
- Potential US Population Impact of the 2017 ACC/AHA...
- Empagliflozin and Clinical Outcomes in Patients Wi...
- Sodium/Glucose Cotransporter 2 Inhibitors in Patie...
- Influence of Baseline Diastolic Blood Pressure on ...
- Benefits and Risks of Antihypertensive Treatment: ...
- Exercise Intolerance in Heart Failure With Preserv...
- Can Oxygen Transport Analysis Tell Us Why People W...
- Extracellular Matrix Proteomics Reveals Interplay ...
- Early Detection of Subclinical Myocardial Damage i...
- High Costs and Caution Yield Slow Start for New He...
- Bayes Syndrome: What Is It?.
- Accelerometer-Measured Physical Activity and Seden...
- Risks of Overinterpreting Interim Data: Lessons Fr...
- Letter by Chen and Shen Regarding Article, "Exosom...
- Response by Marban and de Couto to Letter Regardin...
- Letter by Ianiro et al Regarding Article, "Effect ...
- Letter by Jin-shan and Xue-bin Regarding Article, ...
- Quantitative Analysis Of Lipid Debris Accumulation...
- The effects of melatonin and curcumin on the expre...
- Viable tumor in salvage neck dissections in head a...
- Management of treatment failure in restless legs s...
- Long-term outcomes after percutaneous renal cryoab...
- Sustained improvement of psoriasis associated with...
- Double-balloon enteroscopy (DBE) in patients prese...
- A difficult diagnosis of coeliac disease: Repeat d...
- Inflammation induced ER stress affects absorptive ...
- Quantitative CT Assessment of Gynecomastia in the ...
- Tracking diet variety in childhood and its associa...
- Parental feeding practices to manage snack food in...
- An RNA-seq screen of P. gingivalis LPS treated hum...
- Ultrastructural damage in Streptococcus mutans inc...
- SUPRAGINGIVAL AND SUBGINGIVAL MICROBIOTA FROM PATI...
- BET’ing on Dual JAK/BET Inhibition as a Therapeuti...
- Characterizing the Killer Colorectal Carcinomas
- A TFIID-SAGA Perturbation that Targets MYB and Sup...
- TIM-3 Regulates CD103+ Dendritic Cell Function and...
- Oncogenic KRAS Regulates Amino Acid Homeostasis an...
- Hedgehog Pathway Drives Fusion-Negative Rhabdomyos...
- Clinical Sequencing Defines the Genomic Landscape ...
- Integrative Analysis Identifies Four Molecular and...
- Arid1a Has Context-Dependent Oncogenic and Tumor S...
- Tumor Evolution of Glioma-Intrinsic Gene Expressio...
- 11q23 deletion syndrome (Jacobsen syndrome) with s...
- Anesthesia for Same Day Discharge After Craniotomy...
- Innate Sex Bias of Staphylococcus aureus Skin Infe...
- Ca2+-Dependent Regulation of NFATc1 via KCa3.1 in ...
- Cytoplasmic Linker Protein CLIP170 Negatively Regu...
- Foxp1 Negatively Regulates T Follicular Helper Cel...
- Osteoblasts Are Rapidly Ablated by Virus-Induced S...
- Time-Restricted Feeding Alters the Innate Immune R...
- mPGES1-Dependent Prostaglandin E2 (PGE2) Controls ...
- In This Issue [IN THIS ISSUE]
- Naive CD4+ T Cells Carrying a TLR2 Agonist Overcom...
- Inhibitors of the PD-1 Pathway in Tumor Therapy [T...
- Role of CD44 in Regulating TLR2 Activation of Huma...
- A Believers Overview of Cancer Immunosurveillance ...
- Metformin Mediates Protection against Legionella P...
- Hitting the Target: How T Cells Detect and Elimina...
- A Role of NKR-P1A (CD161) and Lectin-like Transcri...
- Tissue-Resident Cytolytic Innate Lymphocytes in Ca...
- Early Inhibition of Fatty Acid Synthesis Reduces G...
- Alternative Splicing Transcripts of Zebrafish LGP2...
- Immune Cell Infiltration and Tertiary Lymphoid Str...
- Dendritic Cell RIPK1 Maintains Immune Homeostasis ...
- Dendritic Cell-Based Cancer Vaccines [BRIEF REVIEWS]
- Ex-situ Organ Preservation: The Temperature Paradigm
- Liver Simulated Allocation Modeling: Were the Pred...
- The Effects of Short-Term Subnormothermic Perfusio...
- Antioxidant activity of CAPE (caffeic acid pheneth...
- Benign prostatic hyperplasia surgical scoring (BPH...
- Revision Sinus Surgery Sets the Stage for a Succes...
- Under Pressure: On Call During Hurricane Harvey
-
▼
Ιαν 08
(279)
-
►
2017
(111579)
- ► Δεκεμβρίου (7718)
- ► Σεπτεμβρίου (7549)
- ► Φεβρουαρίου (10753)
- ► Ιανουαρίου (10529)
-
►
2016
(16402)
- ► Δεκεμβρίου (7478)
- ► Φεβρουαρίου (900)
- ► Ιανουαρίου (1250)
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου