RNA Selection by PIWI Proteins

Publication date: Available online 24 January 2018
Source:Trends in Biochemical Sciences
Author(s): Alexey L. Arkov
Gene regulation by PIWI–piRNA complexes is determined by the selection of cognate target RNAs by PIWI–piRNA. What are the mechanisms for this selection? There is a rigorous multistep control in identifying target RNAs by PIWI–piRNA structures, and RNA helicases play a potentially crucial role in this process.



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