Determination of the effective dose delivered by image guided radiotherapy in head & neck and breast treatments.

Determination of the effective dose delivered by image guided radiotherapy in head & neck and breast treatments.

Z Med Phys. 2018 Feb 06;:

Authors: Conrad M, Bolard G, Nowak M, De Bari B, Jeanneret-Sozzi W, Bourhis J, Germond JF, Bochud F, Moeckli R

Abstract
PURPOSE: Image guided radiotherapy (IGRT) improves patient positioning for treatment delivery at the cost of an additional dose. This work aimed to calculate the effective dose (as an indicator of dose) for head & neck (H&N) and breast IGRT treatments by implementing dose calculation models to determine the dose distributions.
METHODS: The kV dose-models were created for the IGRT systems of Elekta Synergy (XVI) and Varian Clinac (OBI) linear accelerators within Philips Pinnacle TPS. Profiles and depth dose curves were measured in water. The models were validated in a CIRS thorax phantom. The IGRT dose distributions for five H&N and five breast patients were calculated. The effective dose was determined from the dose distributions following ICRP 103 recommendations. Moreover, time-saving approximations were studied in order to propose an alternative way of segmenting the tissues for a clinical implementation of the method.
RESULTS AND CONCLUSION: The effective dose specifically associated with IGRT varied from 1 to 10mSv depending on the protocol. The kV dose-model allowed us to calculate the dose distributions from IGRT for different configurations and patients, and to determine effective dose for IGRT protocols. The clinical implementation of the method was found to reduce time and to introduce a small enough increase of uncertainty in the results to be clinically usable.

PMID: 29426589 [PubMed - as supplied by publisher]

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