Publication date: Available online 24 March 2018
Source:Clinical Therapeutics
Author(s): Tanya M. Burton, Xin Ye, Emily D. Parker, Tim Bancroft, John Healey
PurposeLittle is known about the burden of illness in patients with tenosynovial giant cell tumors (TGCT), which are rare, typically benign, lesions of the synovial tissue including giant cell tumor of the tendon sheath (GCT-TS) and pigmented villonodular synovitis (PVNS). The objective of this study was to describe health care resource use and costs for patients with GCT-TS and PVNS, which are rare and typically benign TGCT.MethodsA retrospective cohort study design was used to analyze administrative claims for adult commercial and Medicare Advantage health plan enrollees with evidence of GCT-TS and PVNS from January 1, 2006 through March 31, 2015. Participants were continuously enrolled for 12 months before (pre-index period) and 12 months after (post-index period) the date of the first tenosynovial giant cell tumor (TGCT) claim (index date). Preindex and postindex measures were compared using the McNemar test and Wilcoxon signed-rank test. Results were stratified by TGCT type.FindingsThe study identified 4664 patients with TGCT, 284 with GCT-TS, and 4380 with PVNS. Mean age (GCT-TS group: 50 years; PVNS group: 51 years) and sex distributions (GCT-TS group: 60.2% female; PVNS group: 59.5% female) were similar for each group. Most patients with GCT-TS (78.2%) had at least one postindex surgery, compared with 38.7% of patients with PVNS. Mean total health care costs increased from $8943 in the preindex period to $14,880 in the postindex period (P < 0.001) for GCT-TS and from $13,221 in the preindex period to $17,728 in the postindex period (P < 0.001) for PVNS. Preindex to postindex ambulatory costs increased nearly 120% for patients with GCT-TS ($4340 to $9570, P < 0.001) and 50% for patients with PVNS ($6782 to $10,278, P < 0.001), and physical therapy use increased significantly during the same period (GCT-TS: 18% to 40%, P < 0.001; PVNS: 38% to 60%, P < 0.001).ImplicationsCosts increased substantially 1 year after the first TGCT claim, with more than half the costs covering ambulatory care. These results suggest a high health care burden once TGCT is identified.
https://ift.tt/2GntFjO
Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com
Αρχειοθήκη ιστολογίου
-
►
2023
(391)
- ► Φεβρουαρίου (200)
- ► Ιανουαρίου (191)
-
►
2022
(2843)
- ► Δεκεμβρίου (161)
- ► Σεπτεμβρίου (219)
- ► Φεβρουαρίου (264)
- ► Ιανουαρίου (280)
-
►
2021
(5625)
- ► Δεκεμβρίου (231)
- ► Σεπτεμβρίου (345)
- ► Φεβρουαρίου (620)
-
►
2020
(2065)
- ► Δεκεμβρίου (535)
- ► Σεπτεμβρίου (222)
- ► Φεβρουαρίου (28)
-
►
2019
(9608)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (3791)
- ► Ιανουαρίου (3737)
-
▼
2018
(69720)
- ► Δεκεμβρίου (3507)
- ► Σεπτεμβρίου (3851)
-
▼
Μαρτίου
(9878)
-
▼
Μαρ 24
(312)
- Prevalence and molecular characterization of Staph...
- Large herbivores affect forest ecosystem functions...
- Dose escalation for prostate stereotactic ablative...
- Boosting the LTP-like plasticity effect of intermi...
- Environmental asbestos exposure and mesothelioma c...
- Characteristics of arsenic in humic substances ext...
- Fine particulate matter (PM 2.5 ) in a compost fac...
- Suitable flow pattern increases the removal effici...
- Texas Hill Country ENT Symposium Scheduled for Apr...
- Remote sensing of on-road vehicle emissions: Mecha...
- Branchial Cleft Cyst Resection: A Pediatric Patien...
- Determination of respirable-sized crystalline sili...
- Dr. Michael Byrd Named 2017 Physician of the Year ...
- 2017 Lone Star Rhinology Course Recap
- Evaluation of cellular effects of fine particulate...
- Characteristics of atmospheric ammonia and its rel...
- Endoplasmic Reticular–Mitochondrial Contactology: ...
- Modulating ion channel function with antibodies an...
- High performance of 3D porous graphene/lignin/sodi...
- Engineering T cells for adoptive therapy: outsmart...
- Chemokines and cancer: new immune checkpoints for ...
- Diffuse Gastric Ganglioneuromatosis: Novel Present...
- Effect of Cathodal Transcranial Direct Current Sti...
- LEC1 (NF-YB9) directly interacts with LEC2 to cont...
- Quantitative structure–activity relationship for t...
- “Tumulus” stabilization of a total ossicular repla...
- In-clinic secondary tracheoesophageal puncture and...
- Discordance entre SaO2 – PaO2 : ne pas oublier les...
- Monitoring cellular redox state under hypoxia usin...
- Intron-retained transcripts of the spinal muscular...
- Neuroplasticity: the Other Side of the Coin
- The art of imagination
- Discriminability of numerosity-evoked fMRI activit...
- Characterization of rat primary trigeminal satelli...
- Evaluation of some effects on plant metabolism thr...
- A matter of ingredients
- Molecular signatures of medullary thyroid carcinom...
- Loss of PD-L1 (SP-142) expression characterizes re...
- Editorial Board
- Subterranean infestation by Holotrichia parallela ...
- Neural synchronization deficits linked to cortical...
- Phylogenetic relationship of a fossil macaque (Mac...
- Toxicity evaluation of 4,4′-di-CDPS and 4,4′-di-CD...
- Abass Alavi: A giant in Nuclear Medicine turns 80 ...
- Differentiated thyroid cancer and selenium supplem...
- Andersson's lesion in ankylosing spondylitis diagn...
- Simultaneous pulmonary and inferior vena cava tumo...
- 123I-ioflupane SPET and 123I-MIBG in the diagnosis...
- Is there an incremental value to use myocardial pe...
- Correlations between dual-phase 18F-FDG uptake and...
- 18F-FDG PET/CT and ultrasonogrpahy in differentiat...
- Tumoricidal effect and pain relief after concurren...
- Value of 18F-FDG PET/CT in discrimination between ...
- "B-ENT"[jour]; +42 new citations
- Abass Alavi: A giant in Nuclear Medicine turns 80 ...
- Differentiated thyroid cancer and selenium supplem...
- Andersson's lesion in ankylosing spondylitis diagn...
- Inflammatory myofibroblastic tumor mimicking lymph...
- Simultaneous pulmonary and inferior vena cava tumo...
- Long term quality of life in differentiated thyroi...
- 123I-ioflupane SPET and 123I-MIBG in the diagnosis...
- Is there an incremental value to use myocardial pe...
- Is there an association between hibernating myocar...
- Tumoricidal effect and pain relief after concurren...
- Effects of age and weight on the metabolic activit...
- Seeking black. Geochemical characterization by PIX...
- Data set on G4 DNA interactions with human proteins
- Data from RE distressed market: Properties auction...
- A comprehensive diffusion MRI dataset acquired on ...
- Dataset on the piezo-spectroscopic behaviour of hy...
- Microstructural data of six recent brachiopod spec...
- Relationship between intraocular pressure lowering...
- Lactobacillus acidophilus NS1 attenuates diet-indu...
- Fructose bisphosphatase 2 overexpression increases...
- Association between impaired IL-10 production foll...
- An alternative digital workflow for fabricating a ...
- Disseminated cutaneous histoplasmosis with larynge...
- Multicenter phase I/II study of chemoradiotherapy ...
- The 2016 G. Paul Moore Lecture: Lessons in Voice R...
- Comparison of the Dietary Antioxidant Profiles of ...
- A Leadership Taxonomy for Clinical Dietetics Practice
- The genus Datura L. (Solanaceae) in Mexico and Spa...
- Pien-Tze-Huang protects cerebral ischemic injury b...
- Chemical characterization, pharmacological effects...
- Anti-thrombotic and pro-angiogenic effects of Rubi...
- The inhibitory effect of gypenoside stereoisomers,...
- Validation of ethnopharmacology of ayurvedic saras...
- The pharmacological properties of Ophiocordyceps x...
- Reduced heart rate variability and increased saliv...
- Drug Treatment for Androgenetic Alopecia: First It...
- Occupational exposure and asthma
- Barriers to medication adherence in asthma: the im...
- Local Anesthetic Injection Speed and Common Perone...
- HIF stabilizers in the management of renal anemia:...
- Evolving models of collaborative drug discovery: m...
- Overcoming problems of poor drug penetration into ...
- Commentary on “A Feasibility Study of a New Unibod...
- Response to Commentary on “Five-year Results of Gr...
- Myocardial Injury is More Common than Deep Venous ...
- A Feasibility Study of a New Unibody Branched Sten...
-
▼
Μαρ 24
(312)
- ► Φεβρουαρίου (8116)
- ► Ιανουαρίου (7758)
-
►
2017
(111579)
- ► Δεκεμβρίου (7718)
- ► Σεπτεμβρίου (7549)
- ► Φεβρουαρίου (10753)
- ► Ιανουαρίου (10529)
-
►
2016
(16402)
- ► Δεκεμβρίου (7478)
- ► Φεβρουαρίου (900)
- ► Ιανουαρίου (1250)
! # Ola via Alexandros G.Sfakianakis on Inoreader
Η λίστα ιστολογίων μου
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Αρχειοθήκη ιστολογίου
-
►
2023
(391)
- ► Φεβρουαρίου (200)
- ► Ιανουαρίου (191)
-
►
2022
(2843)
- ► Δεκεμβρίου (161)
- ► Σεπτεμβρίου (219)
- ► Φεβρουαρίου (264)
- ► Ιανουαρίου (280)
-
►
2021
(5625)
- ► Δεκεμβρίου (231)
- ► Σεπτεμβρίου (345)
- ► Φεβρουαρίου (620)
-
►
2020
(2065)
- ► Δεκεμβρίου (535)
- ► Σεπτεμβρίου (222)
- ► Φεβρουαρίου (28)
-
►
2019
(9608)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (3791)
- ► Ιανουαρίου (3737)
-
▼
2018
(69720)
- ► Δεκεμβρίου (3507)
- ► Σεπτεμβρίου (3851)
-
▼
Μαρτίου
(9878)
-
▼
Μαρ 24
(312)
- Prevalence and molecular characterization of Staph...
- Large herbivores affect forest ecosystem functions...
- Dose escalation for prostate stereotactic ablative...
- Boosting the LTP-like plasticity effect of intermi...
- Environmental asbestos exposure and mesothelioma c...
- Characteristics of arsenic in humic substances ext...
- Fine particulate matter (PM 2.5 ) in a compost fac...
- Suitable flow pattern increases the removal effici...
- Texas Hill Country ENT Symposium Scheduled for Apr...
- Remote sensing of on-road vehicle emissions: Mecha...
- Branchial Cleft Cyst Resection: A Pediatric Patien...
- Determination of respirable-sized crystalline sili...
- Dr. Michael Byrd Named 2017 Physician of the Year ...
- 2017 Lone Star Rhinology Course Recap
- Evaluation of cellular effects of fine particulate...
- Characteristics of atmospheric ammonia and its rel...
- Endoplasmic Reticular–Mitochondrial Contactology: ...
- Modulating ion channel function with antibodies an...
- High performance of 3D porous graphene/lignin/sodi...
- Engineering T cells for adoptive therapy: outsmart...
- Chemokines and cancer: new immune checkpoints for ...
- Diffuse Gastric Ganglioneuromatosis: Novel Present...
- Effect of Cathodal Transcranial Direct Current Sti...
- LEC1 (NF-YB9) directly interacts with LEC2 to cont...
- Quantitative structure–activity relationship for t...
- “Tumulus” stabilization of a total ossicular repla...
- In-clinic secondary tracheoesophageal puncture and...
- Discordance entre SaO2 – PaO2 : ne pas oublier les...
- Monitoring cellular redox state under hypoxia usin...
- Intron-retained transcripts of the spinal muscular...
- Neuroplasticity: the Other Side of the Coin
- The art of imagination
- Discriminability of numerosity-evoked fMRI activit...
- Characterization of rat primary trigeminal satelli...
- Evaluation of some effects on plant metabolism thr...
- A matter of ingredients
- Molecular signatures of medullary thyroid carcinom...
- Loss of PD-L1 (SP-142) expression characterizes re...
- Editorial Board
- Subterranean infestation by Holotrichia parallela ...
- Neural synchronization deficits linked to cortical...
- Phylogenetic relationship of a fossil macaque (Mac...
- Toxicity evaluation of 4,4′-di-CDPS and 4,4′-di-CD...
- Abass Alavi: A giant in Nuclear Medicine turns 80 ...
- Differentiated thyroid cancer and selenium supplem...
- Andersson's lesion in ankylosing spondylitis diagn...
- Simultaneous pulmonary and inferior vena cava tumo...
- 123I-ioflupane SPET and 123I-MIBG in the diagnosis...
- Is there an incremental value to use myocardial pe...
- Correlations between dual-phase 18F-FDG uptake and...
- 18F-FDG PET/CT and ultrasonogrpahy in differentiat...
- Tumoricidal effect and pain relief after concurren...
- Value of 18F-FDG PET/CT in discrimination between ...
- "B-ENT"[jour]; +42 new citations
- Abass Alavi: A giant in Nuclear Medicine turns 80 ...
- Differentiated thyroid cancer and selenium supplem...
- Andersson's lesion in ankylosing spondylitis diagn...
- Inflammatory myofibroblastic tumor mimicking lymph...
- Simultaneous pulmonary and inferior vena cava tumo...
- Long term quality of life in differentiated thyroi...
- 123I-ioflupane SPET and 123I-MIBG in the diagnosis...
- Is there an incremental value to use myocardial pe...
- Is there an association between hibernating myocar...
- Tumoricidal effect and pain relief after concurren...
- Effects of age and weight on the metabolic activit...
- Seeking black. Geochemical characterization by PIX...
- Data set on G4 DNA interactions with human proteins
- Data from RE distressed market: Properties auction...
- A comprehensive diffusion MRI dataset acquired on ...
- Dataset on the piezo-spectroscopic behaviour of hy...
- Microstructural data of six recent brachiopod spec...
- Relationship between intraocular pressure lowering...
- Lactobacillus acidophilus NS1 attenuates diet-indu...
- Fructose bisphosphatase 2 overexpression increases...
- Association between impaired IL-10 production foll...
- An alternative digital workflow for fabricating a ...
- Disseminated cutaneous histoplasmosis with larynge...
- Multicenter phase I/II study of chemoradiotherapy ...
- The 2016 G. Paul Moore Lecture: Lessons in Voice R...
- Comparison of the Dietary Antioxidant Profiles of ...
- A Leadership Taxonomy for Clinical Dietetics Practice
- The genus Datura L. (Solanaceae) in Mexico and Spa...
- Pien-Tze-Huang protects cerebral ischemic injury b...
- Chemical characterization, pharmacological effects...
- Anti-thrombotic and pro-angiogenic effects of Rubi...
- The inhibitory effect of gypenoside stereoisomers,...
- Validation of ethnopharmacology of ayurvedic saras...
- The pharmacological properties of Ophiocordyceps x...
- Reduced heart rate variability and increased saliv...
- Drug Treatment for Androgenetic Alopecia: First It...
- Occupational exposure and asthma
- Barriers to medication adherence in asthma: the im...
- Local Anesthetic Injection Speed and Common Perone...
- HIF stabilizers in the management of renal anemia:...
- Evolving models of collaborative drug discovery: m...
- Overcoming problems of poor drug penetration into ...
- Commentary on “A Feasibility Study of a New Unibod...
- Response to Commentary on “Five-year Results of Gr...
- Myocardial Injury is More Common than Deep Venous ...
- A Feasibility Study of a New Unibody Branched Sten...
-
▼
Μαρ 24
(312)
- ► Φεβρουαρίου (8116)
- ► Ιανουαρίου (7758)
-
►
2017
(111579)
- ► Δεκεμβρίου (7718)
- ► Σεπτεμβρίου (7549)
- ► Φεβρουαρίου (10753)
- ► Ιανουαρίου (10529)
-
►
2016
(16402)
- ► Δεκεμβρίου (7478)
- ► Φεβρουαρίου (900)
- ► Ιανουαρίου (1250)
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου