In case you missed it – basic science advances in Transplantation 2017

Developments in organ preservation techniques, novel immunosuppressants and improved diagnostics have made organ transplantation the success it is today. That does not mean that we are not still striving to perfect techniques, or that there are no more problems to solve. New strategies to address the donor organ shortage, prevent and manage antibody-mediated rejection, lower long-term allograft failure rates and reduce the toxicity of life-long immunosuppressive medication are urgently needed, and are being widely researched. Both fundamental research and preclinical studies aim to solve these problems and, ultimately, benefit organ transplant recipients. This article highlights the latest technical developments and trends in xenotransplantation, tissue injury and regeneration, immunosuppression, and transplantation immunology described in the most viewed and cited papers published in the Basic Sciences section of the Transplantation journal during the year 2017. Address for correspondence: Carla C. Baan, PhD, Erasmus MC-University Medical Centre, The Rotterdam Transplant Group, Department of Internal Medicine, P.O. Box 2040, Room Nc-508, 3000 CA Rotterdam, The Netherlands. Telephone: +31-10-7038293. T: @BaanCarla / @RotterdamTrans. Email: c.c.baan@erasmusmc.nl Authorship. C C Baan wrote the manuscript. Disclosures. None Funding. None Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.

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