Pattern of presentation of gastroesophageal reflux disease among patients with dyspepsia in Kano, Nigeria.

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Pattern of presentation of gastroesophageal reflux disease among patients with dyspepsia in Kano, Nigeria.

Ann Afr Med. 2017 Oct-Dec;16(4):159-163

Authors: Maiyaki AS, Borodo MM, Samaila AA, Yakubu A

Abstract
BACKGROUND: Dyspepsia is a symptom complex rather than a specific disease entity. It can be caused by both organic and functional gastrointestinal (GI) disorders. Gastroesophageal reflux disease (GORD) though a common digestive disorder worldwide is scarcely reported in Nigeria. The aim of this study is to determine the pattern of presentation of GORD among patients with dyspepsia.
METHODS: One hundred and seventy dyspeptic patients were recruited consecutively as they were referred to the Gastroenterology Unit of Aminu Kano Teaching Hospital for upper GI endoscopy. A prepared questionnaire on relevant demographic and clinical history relating to GORD was administered. Upper GI endoscopy was then performed on each patient.
RESULTS: The prevalence of GORD was 24.1%, with a M:F ratio of 1:1.1. Endoscopy-positive variant accounted for 16 cases (9.4%), while endoscopy-negative variant accounted for 25 cases (14.7%), with of the total GORD patients, 26(63.4%) were males while 15(36.6%) were females. Los Angeles Grade A (37.5%) was the predominant endoscopic esophageal mucosal injury found in 6 cases. Barrett's esophagus and esophageal adenocarcinoma accounted 4.9% each and were considered to be rare. Extra-esophageal manifestations were also rare.
CONCLUSIONS: Endoscopy-negative variant still remains the predominant endoscopic finding in GORD patients.

PMID: 29063898 [PubMed - indexed for MEDLINE]

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