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Effects of Micro RNAs and their targets in periodontal diseases.
Infect Disord Drug Targets. 2018 Apr 05;:
Authors: Bourbour S, Beheshti M, Kazemian H, Bahador A
Abstract
: RNA interference is a strong mechanism of gene silencing which underlies many fields of eukaryotic biology (1). MicroRNAs (miRNAs) are small noncoding RNAs and a gene regulation expression system showing a tissue-specific expression pattern, and inhibits protein synthesis (2). For the first time, miRNA has been seen in Caenorhabditis elegans (3). They play an important role in signaling pathways of various diseases especially periodontal disease and cancers (4). One of the most important diseases in association with gingival infectious is periodontal diseases, which if untreated leads to tooth loss, hence in present paper focus on the effects of MicroRNAs and their targets in disease which was mentioned above.
PMID: 29621968 [PubMed - as supplied by publisher]
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