An allometric approach of tumor-angiogenesis

Publication date: July 2018
Source:Medical Hypotheses, Volume 116
Author(s): Oliver Szasz, Gyula Vincze, Gyula Peter Szigeti, Zoltan Benyo, Andras Szasz
Angiogenesis is one of the main supporting factors of tumor-progression. It is a complex set of interactions together with hypoxia and inflammation, regulating tumor growth. The objective of this study is to examine the effect of angiogenesis with an allometric approach applied to angiogenesis and the regulating factors. The results show that allometry has the potential to describe this aspect, including the sigmoid-like transport function. There are particular conditions under which the complex control maximizes the relative tumor mass. Linear growth of malignancy diameter with an allometric approach was proven.



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