Olfactory dysfunction out of season in seasonal allergic rhinitis

Olfactory dysfunction (OD) is one of the major symptoms caused by seasonal allergic rhinitis (AR).1 It has been reported that in allergic rhinitis, inflammatory cells infiltrate the olfactory mucosa.2 Moll et al.3 showed that the extra-seasonal score in the 1-butanol threshold test of patients with grass pollen allergy was lower than that of control subjects. It was also reported that all patients had normal olfactory function (OF) prior to the season.1 It is therefore unclear whether OD persists out of pollen season in patients with seasonal AR, especially in patients who do not complain of OD.

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