FPIES in Adults

Non-IgE-mediated food allergic disorders are poorly characterized in adults. Some adult patients report gastrointestinal (GI) symptoms that recur consistently after ingestion of specific foods, in the absence of cutaneous, respiratory or cardiovascular manifestations. These patients have no evidence of food-specific IgE, either by in vivo or in vitro testing. It has been speculated that these patients have an adult variant of food protein-induced enterocolitis syndrome (FPIES), which is a non-IgE-mediated food hypersensitivity, generally diagnosed in infants1.

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