Advances in Atopic Dermatitis in 2017

Publication date: Available online 22 October 2018

Source: Journal of Allergy and Clinical Immunology

Author(s): Katie Kennedy, Jennifer Heimall, Jonathan M. Spergel

Synopsis

This review encompasses relevant scientific and clinical advances in atopic dermatitis published in 2017. These include articles from the Journal as well as other prominent publications that have contributed to the emerging field of the microenvironment of the skin and molecular patterns guiding biologic treatment strategies. The most commonly questioned and explored themes of the year included the impact of the microbiome on atopic dermatitis development as well as cell signaling and severity of symptoms. Topics also included the description of patient specific molecular endotypes within the larger atopic dermatitis population. All of these factors will create potential opportunities to guide personalized therapy with the broadening array of topical and systemic interventions currently available, as well as provide new insights to guide development of novel, molecularly targeted therapeutics. With recent FDA approval of the first wave of new, targeted therapies for atopic dermatitis (AD), additional information exploring the safety profiles and long-term effects of these medications was also at the forefront of 2017.

https://ift.tt/2AmHQSn