Virulent Staphylococcus lugdunensis with limited genetic diversity in hidradenitis suppurativa lesions

Abstract

Hidradenitis suppurativa (HS) is an inflammatory skin disease characterized by recurring painful, deep‐seated inflammatory nodules, abscesses, sinus tracts, and scarring in the intertriginous areas. Bacteria may be involved in the pathogenesis of HS via follicular dysbiosis in the initial stages, and via biofilm in chronic sinus tracts. Staphylococcus lugdunensis, a coagulase‐negative staphylococcus (CNS), has been cultured from hidradenitis suppurativa nodules and abscesses. This points towards a role of S. lugdunensis in the aggravation and secondary colonization of HS lesions.

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