48-year-old patient with a 20-year histo...

General Practice     CASE   Treatment of auditory verbal hallucinations with transcranial magnetic stimulation in a patient with psychotic major depression: one-year follow-up. Auditory verbal hallucinations (AVH) in patients with schizophrenia can respond to repetitive transcranial magnetic stimulation (TMS). We report the therapeutic utility of rTMS in a 48-year-old patient with a 20-year history of severe depression (five suicidal gestures and previous failure of ECT) and internal AVH. First, 20 Hz rTMS to the left prefrontal cortex for 3 weeks significantly improved depression (BDI-II: 89% change, lasting 14 months along with weekly/bi-weekly maintenance treatments), but AVH remained unchanged. The patient also underwent a further course of the left temporo-parietal 1 Hz rTMS and amelioration of AVH severity was achieved (PSYRATS-AH: 53% change) and maintained at 1-year follow-up. AVH respond to rTMS in disorders other than schizophrenia. Furthermore, targeted rTMS to different brain regions can address diverse symptoms in neuropsychiatric conditions.   What would you do next?   from: Berenson-Allen Center for Noninvasive Brain Stimulation, Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA. as reported in: Freitas C, Pearlman C, Pascual-Leone A. Neurocase. 2012 Feb:18(1):57-65. doi: 10.1080/13554794.2010.547864. See Published Case Report   Post an interesting case and share it with your colleagues to get feedback Post a Case | My Cases SPONSORED SPONSORED DG Cases improves your diagnostic acuity and clinical decision making skills by letting you review and participate in online cases. SEND FEEDBACK © 2015 Doctor's Guide Publishing Limited. All rights reserved. 1140 Avenue of the Americas, 14th Floor New York, NY 10036 Change your password Edit Profile |  Terms of Use |  Privacy Policy |  Unsubscribe

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