Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
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alsfakia@gmail.com

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Τετάρτη 13 Ιανουαρίου 2016

Administration of Ethanolic Extract of Ocimum Basilicum Leaves Attenuates Depression like Behavior in the Rats Sensitized by Ovalbumin

A relationship between inflammation and depression has been suggested. Ocimum basilicum, has been reported to have preventive effects of inflammatory responses. The aim of this study was to evaluate the effects of hydro-ethanolic extract of Ocimum basilicum leaves on depressive behaviors in rats sensitized by ovalbumin. The animals were grouped into: (1) Control: saline was injected, (2) Sensitized: sensitization was carried out by ovalbumin, (3-5) three groups including Sent-Ocim 50, Sent- Ocim 100 and Sent- Ocim 200 : sensitization was carried and also 50, 100 or 200 mg/kg, of Ocimum basilicum leave extract was injected. In open- field (O-F) test, the number of crossing in the central zone of the sensitized group was lower while, the number of crossing in the peripheral zone was higher…

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