Reverse fluorescein cap sign of cavernous haemangioma of optic nerve on OCT angiography

Description

A man aged 57 years, a known hypertensive, presented with symptoms of visual loss in the upper field in the left eye since 6 months. Best-corrected visual acuity in both eyes was 20/20, N6 (with eccentric fixation in the left eye). On clinical examination, he was found to have a vascular malformation of the optic nerve head (ONH) with typical grape clusters appearance of ONH in both eyes, suggestive of cavernous haemangioma and associated inferotemporal branch retinal artery occlusion corresponding to the upper visual field defect in the left eye.

Cavernous haemangioma is a non-progressive rare retinal vascular hamartoma. Typical fundus findings are clumps of dark saccular aneurysms (cluster of grapes appearance) with fibroglial tissue over the tumour, absence of feeder vessels and absence of exudation. Complications include haemorrhage and retinal arterial occlusions.12 Diagnosis is based on clinical picture and typical fluorescein cap sign...

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