Local inflammation exacerbates cutaneous manifestations in a murine autoimmune pemphigus model

Publication date: Available online 20 January 2017
Source:Journal of Allergy and Clinical Immunology
Author(s): Sachiko Ono, Gyohei Egawa, Akihiko Kitoh, Teruki Dainichi, Atsushi Otsuka, Saeko Nakajima, Tetsuya Honda, Kenji Kabashima

Teaser

Capsule summary: Local inflammation enhances autoantibody deposition in the skin and exacerbates murine pemphigus manifestations as a representative of autoantibody-mediated disorders, therefore prevention of excessive external stimulants might be important for the disease management.


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