Position statement of the Brazilian Academy of Rhinology on the use of antihistamines, antileukotrienes, and oral corticosteroids in the treatment of inflammatory sinonasal diseases

Publication date: Available online 21 January 2017
Source:Brazilian Journal of Otorhinolaryngology
Author(s): Olavo de Godoy Mion, João Ferreira de Mello, Daniel Lorena Dutra, Nilvano Alves de Andrade, Washington Luiz de Cerqueira Almeida, Wilma Teresinha Anselmo-Lima, Leonardo Lopes Balsalobre Filho, Jair de Carvalho e Castro, Roberto Eustáquio dos Santos Guimarães, Marcus Miranda Lessa, Sérgio Fabrício Maniglia, Roberto Campos Meireles, Márcio Nakanishi, Shirley Shizue Nagata Pignatari, Renato Roithmann, Fabrizio Ricci Romano, Rodrigo de Paula Santos, Marco César Jorge dos Santos, Edwin Tamashiro
IntroductionInflammatory conditions of the nose and paranasal sinuses are very prevalent in the general population, resulting in marked loss of quality of life in affected patients, as well as significant work, leisure, and social activity losses. These patients require specific and specialized treatment. A wide range of oral medications are available.ObjectiveThe present document is aimed to clarify, for professionals treating patients with inflammatory sinonasal diseases, both specialists and general practitioners, specific oral therapies in noninfectious nasal inflammatory conditions.MethodsThe methodology used to create this article included the search for the key words: oral corticosteroids, antihistamines, antileukotrienes, rhinitis, rhinosinusitis in the MEDLINE and EMBASE databases in the last 5 years. Since no relevant article was found for the text on the subject of interest in the last 5 years, the search was extended for another 5 years, and so on, according to the authors' needs.ResultsRelevant literature was found regarding the use of antihistamines, antileukotrienes and oral corticosteroids in these conditions. The Brazilian Academy of Rhinology emphasizes, after extensive discussion by the collegiate, key points in the treatment with these drugs.ConclusionThere is support in the literature for the use of these drugs; however, final considerations about the role of each of them have been made.



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