Prevalence of Calcified Carotid Artery Atheromas on Panoramic Images of Older Men with Gout: a Descriptive Retrospective Study.

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Prevalence of Calcified Carotid Artery Atheromas on Panoramic Images of Older Men with Gout: a Descriptive Retrospective Study.

Dentomaxillofac Radiol. 2017 Feb 10;:20160406

Authors: Friedlander AH, Graves LL, Grabich SC, Aghazadeh-Sanai N, Chang TI

Abstract
OBJECTIVES: Given the enhanced risk of ischemic stroke resulting from the direct effects of hyperuricemia on vascular plaque formation seen among older males with gout we sought to determine the prevalence of calcified carotid artery atheromas (CCAA) on their panoramic images.
METHODS: Medical records librarians identified all male patients over age 45 who had a diagnosis of gout and a panoramic image incidentally obtained between 2000-2015. The prevalence rate of CCAA on technically appropriate images was determined as were these patients' atherogenic risk profiles including: age, BMI, hypertension, dyslipidemia. Comparisons of atherogenic risk factors were made between this cohort and those without CCAA.
RESULTS: Of the 531 patients with gout, 163 were adjudicated to be CCAA+. Logistic regression analysis demonstrated that a comorbid diagnosis of diabetes mellitus or dyslipidemia, or advancing age was determinant in differentiating patients who were CCAA+ vs. those who were CCAA-.
CONCLUSIONS: Calcified carotid artery atheromas often herald an ischemic stroke and may be seen on the panoramic images of patients with gout, especially those with increased age, dyslipidemia, or diabetes. Thus, dentists must be uniquely vigilant in detecting these lesions when evaluating the images of all patients with gout, especially those with additional positive risk factors.

PMID: 28186844 [PubMed - as supplied by publisher]

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