Publication date: April 2017
Source:Neurobiology of Aging, Volume 52
Author(s): Giovanni B. Frisoni, Daniela Perani, Stefano Bastianello, Gaetano Bernardi, Corinna Porteri, Marina Boccardi, Stefano F. Cappa, Marco Trabucchi, Alessandro Padovani
Biomarkers of brain amyloidosis and neurodegeneration/synaptic dysfunction are featured in recent diagnostic criteria for Alzheimer's disease. Several gaps in our knowledge, however, need to be filled before they can be adopted clinically. The aim of this article is to describe a roadmap, developed by a multidisciplinary task force, to rationally implement biomarkers for Italian Memory Clinics. This roadmap is based on a framework comprising 5 sequential phases: identification of leads for potentially useful biomarkers; development of clinical assays for clinical disease; evaluation of detection of early stages; definition of operating characteristics in relevant populations; and estimation of reducing disease-associated mortality, morbidity, and disability. The roadmap was devised by identifying current evidence of validity, still missing evidence, and action needed to collect this missing evidence. With appropriate adaptation to local, country-specific circumstances, the roadmap can be translated to other countries.
http://ift.tt/2m8LcD6
Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com
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! # Ola via Alexandros G.Sfakianakis on Inoreader
Η λίστα ιστολογίων μου
Παρασκευή 17 Μαρτίου 2017
Biomarkers for the diagnosis of Alzheimer's disease in clinical practice: an Italian intersocietal roadmap
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- Poly(tetrafluoroethylene-hexafluoropropylene) film...
- Molecular dynamics modeling of PPTA crystallite me...
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- A cross-sectional comparison of ethanol-related cy...
- Anaesthesia in patients with liver disease.
- Anesthesia in adults with congenital heart disease.
- Training future anesthesiologists in obstetric care.
- Update in pediatric anesthesiology.
- The American College of Surgeons Children's Surger...
- Fe(III)-based metal–organic framework-derived core...
- A new amplified π-shape electrochemical aptasensor...
- Sensitivity enhancement of graphene/zinc oxide nan...
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- Oxford Textbook of Obstetric Anaesthesia.
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- Oxford Textbook of Obstetric Anaesthesia.
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- Hypersensitivity Pneumonitis in an 11-Year-Old Boy...
- Decreased Expression of B cell Maturation Antigen ...
- Pediatric Allergy, Immunology and Pulmonology Cele...
- Smoking Patterns and Perspectives of Families of I...
- Hypersensitivity Pneumonitis in an 11-Year-Old Boy...
- Decreased Expression of B cell Maturation Antigen ...
- Pediatric Allergy, Immunology and Pulmonology Cele...
- Smoking Patterns and Perspectives of Families of I...
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- Increase of body mass index (BMI) from 1.5 to 3 ye...
- A cross-sectional survey of the nature and correla...
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- Cochlear Transcriptome Following Acoustic Trauma a...
- Tests of Eustachian Tube Function: the Effect of T...
- Secondary Endolymphatic Hydrops.
- New Scoring System for Evaluating Patulous Eustach...
- A cross-sectional survey of the nature and correla...
- A chronic recurrent disease course of dermatomyosi...
- A preliminary investigation of noise impact within...
- Sorption and desorption of silver ions by bentonit...
- Dynamics of biochemical properties associated with...
- Degradation of n -alkanes and PAHs from the heavy ...
- Exploiting fruit byproducts for eco-friendly nanos...
- Determination of heavy metals in muscle tissue of ...
- Spatial distribution, ecological risk assessment, ...
- Spatiotemporal variability in salinity and hydraul...
- Nipple reconstruction with complementary triangula...
- Effect of acidity of in-office bleaching gels on t...
- Fully automated VMAT treatment planning for advanc...
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