<span class="paragraphSection"><div class="boxTitle">Abstract</div>Amyotrophic lateral sclerosis (ALS) may be associated with low body mass index (BMI) at the time of diagnosis. However, the role of premorbid BMI in the development of ALS and survival after diagnosis remains unclear. In 2005–2010, we interviewed 467 patients with ALS from the US National Registry of Veterans with ALS and 975 frequency-matched veteran controls. In this sample, we evaluated the association of BMI and BMI change at different ages with ALS risk using unconditional logistic models and with survival after ALS diagnosis using Cox proportional hazards models. After adjustment for confounders, compared with a moderate increase in BMI between ages 25 and 40 years, stable or decreasing BMI was positively associated with ALS risk (odds ratio (OR) = 1.61, 95% confidence interval (CI): 1.20, 2.16). A 1-unit increase in BMI at age 40 years (OR = 0.95, 95% CI: 0.91, 0.98) but not at age 25 years (OR = 0.99, 95% CI: 0.95, 1.03) was inversely associated with ALS. These associations were similar for bulbar and spinal ALS but stronger for those with a delay of less than 1 year between symptom onset and diagnosis. We found no association between prediagnosis BMI and survival. A decreasing BMI from early to middle age and a low BMI in middle age may be positively associated with ALS risk.</span>
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Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com
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Τετάρτη 1 Μαρτίου 2017
Body Mass Index and Amyotrophic Lateral Sclerosis: A Study of US Military Veterans
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- Bean peptides have higher in silico binding affini...
- Genetics of Congenital Adrenal Hyperplasia
- Trace element composition of smolt scales from Atl...
- Sonochemical synthesis and characterization of mic...
- Evaluation of the bioaccessible gastric and intest...
- The off-stoichiometry effect on the optical proper...
- Synthesis, crystal structure, and luminescent prop...
- Synthesis, characterization, spectral, thermal ana...
- High performance and prospective application of xa...
- The Lymphatic Anatomy of the Lower Eyelid and Conj...
- Abstracts
- The genetics of brain function and psychophysiolog...
- Acoustic Behavior of Halobacterium salinarum Gas V...
- Mutation analysis of CTNNB1 gene and the ras pathw...
- Influence of third molars in mandibular fractures....
- Papilla and alveolar crest levels in immediate ver...
- Papillary carcinoma in struma ovarii
- A rare case of spontaneous Cushing disease remissi...
- The mystery of puberty initiation: genetics and ep...
- A modified intraoral and extraoral approach osteot...
- Correction of tuberous breast deformity: a retrosp...
- Engineered microenvironments for synergistic VEGF ...
- Impact of caries and dental fluorosis on oral heal...
- Idiopathic avascular necrosis associated with humo...
- Evaluation of the risk of infection associated wit...
- Idiopathic avascular necrosis associated with humo...
- Evaluation of the risk of infection associated wit...
- Editorial Board
- Instructions for Authors
- 2016 SRS Presidential Address
- Table of Contents
- Art Is Long, Life Is Short: Lessons Learned in the...
- Masthead
- Report of the 2016 SRS Traveling Fellowship
- Influence of Sequential Ponte Osteotomies on the H...
- Current Evidence Regarding Diagnostic Imaging Meth...
- Scoliosis and the Social Media: Facebook as a Mean...
- Can Postoperative Radiographs Accurately Identify ...
- Prognosis of Significant Intraoperative Neurophysi...
- MRI Screening in Operative Scheuermann Kyphosis: I...
- Benign Natural History of Spondylolysis in Adolesc...
- Predictors of Health-Related Quality-of-Life After...
- Timing of Complications Occurring Within 30 Days A...
- Quality assurance guidelines for superficial hyper...
- Consensus statement for the treatment of infantile...
- Burden of human scabies in sub-Saharan African pri...
- Consensus statement for the treatment of infantile...
- Burden of human scabies in sub-Saharan African pri...
- Suction blistering the lesional skin of vitiligo p...
- Macrophage and osteoclast polarization in bisphosp...
- Gene expression profiling of circulating CD133+ ce...
- Prognostic significance of epithelial/stromal cave...
- Resurrection of whole liver radiotherapy—A case re...
- Malignant peripheral nerve sheath tumor of the ton...
- Spectrum of fungal infection in head and neck canc...
- Sequential curing of thiol-acetoacetate-acrylate t...
- In-situ orientation and crystal growth kinetics of...
- Morphologies of spherical polyampholyte brushes: E...
- Multidimensional Assessment of the Effectiveness o...
- Anatomic distribution of cervicofacial lymphatic m...
- Self-reported postoperative recovery in children a...
- Syk expression and IgE-mediated histamine release ...
- Susceptibility to influenza virus infection of bro...
- Human passive cutaneous anaphylaxis in the 21st ce...
- Plasma apolipoproteins and physical and cognitive ...
- CPAP Treatment Adherence in Women with Obstructive...
- A Wandering Abdominal Mass in a Neonate: An Enteri...
- In Situ Splitting of a Rib Bone Graft for Reconstr...
- Pancreas Transplantation Delays the Progression of...
- Liver radiofrequency ablation as emergency treatme...
- Theoretical Implications of Oxygenation in Limb Re...
- Aging Effect on Categorical Perception of Mandarin...
- Multicenter, randomized, open-label Phase II study...
- Editorial Board
- General and emotion-specific neural effects of ket...
- Fetal Imaging, Other Infectious Diseases Screening...
- GABAA receptor subtypes in the mouse brain: Region...
- Involuntary orienting of attention to a sound desy...
- Aflatoxins, discolouration and insect damage in dr...
- Liver radiofrequency ablation as emergency treatme...
- Mass Spectrometry Imaging Can Distinguish on a Pro...
- Nonhealing Ulcerated Nodules in a Sporotrichoid Pa...
- Nonhealing Ulcerated Nodules in a Sporotrichoid Pa...
- Hydroa Vacciniforme-Like T-Cell Lymphoma: A Furthe...
- Intraepithelial Melanoma in the Stomach After Trea...
- Psychische Verfassung und psychosoziale Versorgung...
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- IL Second counts
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- Unusual extramedullary hematopoietic neoplasms in ...
- Association between promoter methylation of DAPK g...
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