Erythema Nodosum in Association with Idiopathic Granulomatous Mastitis: A Case Series and Review of the Literature

Abstract

Idiopathic granulomatous mastitis (IGM) is a chronic inflammatory disease characterized by tender, erythematous, indurated breast plaques with associated edema, drainage, and scar formation.¹ IGM is often mistaken for breast carcinoma or infectious mastitis.^1,2 Histopathology readily distinguishes IGM from breast carcinoma, as the primary finding in IGM is granulomas centered around mammary lobules.³ Nevertheless, differentiating IGM from bacterial mastitis and other mimickers, such as atypical mycobacterial infections or sarcoidosis, can be more difficult.⁴ Herein, we report the largest case series of concurrent IGM and erythema nodosum (EN).

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