Publication date: Available online 28 February 2017
Source:Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
Author(s): Marco Antonio Briones-Orta, S. Eréndira Avendaño-Vázquez, Diana Ivette Aparicio-Bautista, Jason D. Coombes, Georg F. Weber, Wing-Kin Syn
Osteopontin (OPN) is an extracellular matrix protein that is overexpressed in various cancers and promotes oncogenic features including cell proliferation, survival, migration, and angiogenesis, among others. OPN can participate in the regulation of the tumor microenvironment, affecting both cancer and neighboring cells. Here, we reviewed the roles of OPN splice variants (a, b, c) in cancer development, progression, and prognosis, and also discussed the identities of isoforms 4 and 5. We also discussed how single-nucleotide polymorphisms (SNPs) of the OPN gene are an additional factor influencing the level of OPN in individuals, modulating the risks of cancer development and outcome.
http://ift.tt/2lxKlaA
Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com
Αρχειοθήκη ιστολογίου
-
►
2023
(391)
- ► Φεβρουαρίου (200)
- ► Ιανουαρίου (191)
-
►
2022
(2843)
- ► Δεκεμβρίου (161)
- ► Σεπτεμβρίου (219)
- ► Φεβρουαρίου (264)
- ► Ιανουαρίου (280)
-
►
2021
(5625)
- ► Δεκεμβρίου (231)
- ► Σεπτεμβρίου (345)
- ► Φεβρουαρίου (620)
-
►
2020
(2065)
- ► Δεκεμβρίου (535)
- ► Σεπτεμβρίου (222)
- ► Φεβρουαρίου (28)
-
►
2019
(9608)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (3791)
- ► Ιανουαρίου (3737)
-
►
2018
(69720)
- ► Δεκεμβρίου (3507)
- ► Σεπτεμβρίου (3851)
- ► Φεβρουαρίου (8116)
- ► Ιανουαρίου (7758)
-
▼
2017
(111579)
- ► Δεκεμβρίου (7718)
- ► Σεπτεμβρίου (7549)
-
▼
Μαρτίου
(11966)
-
▼
Μαρ 01
(406)
- An analysis of knowledge-based planning for stereo...
- Bean peptides have higher in silico binding affini...
- Genetics of Congenital Adrenal Hyperplasia
- Trace element composition of smolt scales from Atl...
- Sonochemical synthesis and characterization of mic...
- Evaluation of the bioaccessible gastric and intest...
- The off-stoichiometry effect on the optical proper...
- Synthesis, crystal structure, and luminescent prop...
- Synthesis, characterization, spectral, thermal ana...
- High performance and prospective application of xa...
- The Lymphatic Anatomy of the Lower Eyelid and Conj...
- Abstracts
- The genetics of brain function and psychophysiolog...
- Acoustic Behavior of Halobacterium salinarum Gas V...
- Mutation analysis of CTNNB1 gene and the ras pathw...
- Influence of third molars in mandibular fractures....
- Papilla and alveolar crest levels in immediate ver...
- Papillary carcinoma in struma ovarii
- A rare case of spontaneous Cushing disease remissi...
- The mystery of puberty initiation: genetics and ep...
- A modified intraoral and extraoral approach osteot...
- Correction of tuberous breast deformity: a retrosp...
- Engineered microenvironments for synergistic VEGF ...
- Impact of caries and dental fluorosis on oral heal...
- Idiopathic avascular necrosis associated with humo...
- Evaluation of the risk of infection associated wit...
- Idiopathic avascular necrosis associated with humo...
- Evaluation of the risk of infection associated wit...
- Editorial Board
- Instructions for Authors
- 2016 SRS Presidential Address
- Table of Contents
- Art Is Long, Life Is Short: Lessons Learned in the...
- Masthead
- Report of the 2016 SRS Traveling Fellowship
- Influence of Sequential Ponte Osteotomies on the H...
- Current Evidence Regarding Diagnostic Imaging Meth...
- Scoliosis and the Social Media: Facebook as a Mean...
- Can Postoperative Radiographs Accurately Identify ...
- Prognosis of Significant Intraoperative Neurophysi...
- MRI Screening in Operative Scheuermann Kyphosis: I...
- Benign Natural History of Spondylolysis in Adolesc...
- Predictors of Health-Related Quality-of-Life After...
- Timing of Complications Occurring Within 30 Days A...
- Quality assurance guidelines for superficial hyper...
- Consensus statement for the treatment of infantile...
- Burden of human scabies in sub-Saharan African pri...
- Consensus statement for the treatment of infantile...
- Burden of human scabies in sub-Saharan African pri...
- Suction blistering the lesional skin of vitiligo p...
- Macrophage and osteoclast polarization in bisphosp...
- Gene expression profiling of circulating CD133+ ce...
- Prognostic significance of epithelial/stromal cave...
- Resurrection of whole liver radiotherapy—A case re...
- Malignant peripheral nerve sheath tumor of the ton...
- Spectrum of fungal infection in head and neck canc...
- Sequential curing of thiol-acetoacetate-acrylate t...
- In-situ orientation and crystal growth kinetics of...
- Morphologies of spherical polyampholyte brushes: E...
- Multidimensional Assessment of the Effectiveness o...
- Anatomic distribution of cervicofacial lymphatic m...
- Self-reported postoperative recovery in children a...
- Syk expression and IgE-mediated histamine release ...
- Susceptibility to influenza virus infection of bro...
- Human passive cutaneous anaphylaxis in the 21st ce...
- Plasma apolipoproteins and physical and cognitive ...
- CPAP Treatment Adherence in Women with Obstructive...
- A Wandering Abdominal Mass in a Neonate: An Enteri...
- In Situ Splitting of a Rib Bone Graft for Reconstr...
- Pancreas Transplantation Delays the Progression of...
- Liver radiofrequency ablation as emergency treatme...
- Theoretical Implications of Oxygenation in Limb Re...
- Aging Effect on Categorical Perception of Mandarin...
- Multicenter, randomized, open-label Phase II study...
- Editorial Board
- General and emotion-specific neural effects of ket...
- Fetal Imaging, Other Infectious Diseases Screening...
- GABAA receptor subtypes in the mouse brain: Region...
- Involuntary orienting of attention to a sound desy...
- Aflatoxins, discolouration and insect damage in dr...
- Liver radiofrequency ablation as emergency treatme...
- Mass Spectrometry Imaging Can Distinguish on a Pro...
- Nonhealing Ulcerated Nodules in a Sporotrichoid Pa...
- Nonhealing Ulcerated Nodules in a Sporotrichoid Pa...
- Hydroa Vacciniforme-Like T-Cell Lymphoma: A Furthe...
- Intraepithelial Melanoma in the Stomach After Trea...
- Psychische Verfassung und psychosoziale Versorgung...
- History and epidemiology of anabolic androgens in ...
- IL Second counts
- Association between promoter methylation of DAPK g...
- Unusual extramedullary hematopoietic neoplasms in ...
- Association between promoter methylation of DAPK g...
- Differential regulation analysis reveals dysfuncti...
- Chronic Treatment with Minoxidil Induces Elastic F...
- Norepinephrine Intermittent Intravenous Boluses to...
- Topical agents for oral cancer chemoprevention: A ...
- Combining cetuximab with chemoradiotherapy in pati...
- Stacey Layman DDS – Pulse Oximetry as a Screening ...
- Contents
- Forthcoming Events
-
▼
Μαρ 01
(406)
- ► Φεβρουαρίου (10753)
- ► Ιανουαρίου (10529)
-
►
2016
(16402)
- ► Δεκεμβρίου (7478)
- ► Φεβρουαρίου (900)
- ► Ιανουαρίου (1250)
! # Ola via Alexandros G.Sfakianakis on Inoreader
Η λίστα ιστολογίων μου
Τετάρτη 1 Μαρτίου 2017
Osteopontin splice variants and polymorphisms in Cancer Progression and Prognosis
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Αρχειοθήκη ιστολογίου
-
►
2023
(391)
- ► Φεβρουαρίου (200)
- ► Ιανουαρίου (191)
-
►
2022
(2843)
- ► Δεκεμβρίου (161)
- ► Σεπτεμβρίου (219)
- ► Φεβρουαρίου (264)
- ► Ιανουαρίου (280)
-
►
2021
(5625)
- ► Δεκεμβρίου (231)
- ► Σεπτεμβρίου (345)
- ► Φεβρουαρίου (620)
-
►
2020
(2065)
- ► Δεκεμβρίου (535)
- ► Σεπτεμβρίου (222)
- ► Φεβρουαρίου (28)
-
►
2019
(9608)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (3791)
- ► Ιανουαρίου (3737)
-
►
2018
(69720)
- ► Δεκεμβρίου (3507)
- ► Σεπτεμβρίου (3851)
- ► Φεβρουαρίου (8116)
- ► Ιανουαρίου (7758)
-
▼
2017
(111579)
- ► Δεκεμβρίου (7718)
- ► Σεπτεμβρίου (7549)
-
▼
Μαρτίου
(11966)
-
▼
Μαρ 01
(406)
- An analysis of knowledge-based planning for stereo...
- Bean peptides have higher in silico binding affini...
- Genetics of Congenital Adrenal Hyperplasia
- Trace element composition of smolt scales from Atl...
- Sonochemical synthesis and characterization of mic...
- Evaluation of the bioaccessible gastric and intest...
- The off-stoichiometry effect on the optical proper...
- Synthesis, crystal structure, and luminescent prop...
- Synthesis, characterization, spectral, thermal ana...
- High performance and prospective application of xa...
- The Lymphatic Anatomy of the Lower Eyelid and Conj...
- Abstracts
- The genetics of brain function and psychophysiolog...
- Acoustic Behavior of Halobacterium salinarum Gas V...
- Mutation analysis of CTNNB1 gene and the ras pathw...
- Influence of third molars in mandibular fractures....
- Papilla and alveolar crest levels in immediate ver...
- Papillary carcinoma in struma ovarii
- A rare case of spontaneous Cushing disease remissi...
- The mystery of puberty initiation: genetics and ep...
- A modified intraoral and extraoral approach osteot...
- Correction of tuberous breast deformity: a retrosp...
- Engineered microenvironments for synergistic VEGF ...
- Impact of caries and dental fluorosis on oral heal...
- Idiopathic avascular necrosis associated with humo...
- Evaluation of the risk of infection associated wit...
- Idiopathic avascular necrosis associated with humo...
- Evaluation of the risk of infection associated wit...
- Editorial Board
- Instructions for Authors
- 2016 SRS Presidential Address
- Table of Contents
- Art Is Long, Life Is Short: Lessons Learned in the...
- Masthead
- Report of the 2016 SRS Traveling Fellowship
- Influence of Sequential Ponte Osteotomies on the H...
- Current Evidence Regarding Diagnostic Imaging Meth...
- Scoliosis and the Social Media: Facebook as a Mean...
- Can Postoperative Radiographs Accurately Identify ...
- Prognosis of Significant Intraoperative Neurophysi...
- MRI Screening in Operative Scheuermann Kyphosis: I...
- Benign Natural History of Spondylolysis in Adolesc...
- Predictors of Health-Related Quality-of-Life After...
- Timing of Complications Occurring Within 30 Days A...
- Quality assurance guidelines for superficial hyper...
- Consensus statement for the treatment of infantile...
- Burden of human scabies in sub-Saharan African pri...
- Consensus statement for the treatment of infantile...
- Burden of human scabies in sub-Saharan African pri...
- Suction blistering the lesional skin of vitiligo p...
- Macrophage and osteoclast polarization in bisphosp...
- Gene expression profiling of circulating CD133+ ce...
- Prognostic significance of epithelial/stromal cave...
- Resurrection of whole liver radiotherapy—A case re...
- Malignant peripheral nerve sheath tumor of the ton...
- Spectrum of fungal infection in head and neck canc...
- Sequential curing of thiol-acetoacetate-acrylate t...
- In-situ orientation and crystal growth kinetics of...
- Morphologies of spherical polyampholyte brushes: E...
- Multidimensional Assessment of the Effectiveness o...
- Anatomic distribution of cervicofacial lymphatic m...
- Self-reported postoperative recovery in children a...
- Syk expression and IgE-mediated histamine release ...
- Susceptibility to influenza virus infection of bro...
- Human passive cutaneous anaphylaxis in the 21st ce...
- Plasma apolipoproteins and physical and cognitive ...
- CPAP Treatment Adherence in Women with Obstructive...
- A Wandering Abdominal Mass in a Neonate: An Enteri...
- In Situ Splitting of a Rib Bone Graft for Reconstr...
- Pancreas Transplantation Delays the Progression of...
- Liver radiofrequency ablation as emergency treatme...
- Theoretical Implications of Oxygenation in Limb Re...
- Aging Effect on Categorical Perception of Mandarin...
- Multicenter, randomized, open-label Phase II study...
- Editorial Board
- General and emotion-specific neural effects of ket...
- Fetal Imaging, Other Infectious Diseases Screening...
- GABAA receptor subtypes in the mouse brain: Region...
- Involuntary orienting of attention to a sound desy...
- Aflatoxins, discolouration and insect damage in dr...
- Liver radiofrequency ablation as emergency treatme...
- Mass Spectrometry Imaging Can Distinguish on a Pro...
- Nonhealing Ulcerated Nodules in a Sporotrichoid Pa...
- Nonhealing Ulcerated Nodules in a Sporotrichoid Pa...
- Hydroa Vacciniforme-Like T-Cell Lymphoma: A Furthe...
- Intraepithelial Melanoma in the Stomach After Trea...
- Psychische Verfassung und psychosoziale Versorgung...
- History and epidemiology of anabolic androgens in ...
- IL Second counts
- Association between promoter methylation of DAPK g...
- Unusual extramedullary hematopoietic neoplasms in ...
- Association between promoter methylation of DAPK g...
- Differential regulation analysis reveals dysfuncti...
- Chronic Treatment with Minoxidil Induces Elastic F...
- Norepinephrine Intermittent Intravenous Boluses to...
- Topical agents for oral cancer chemoprevention: A ...
- Combining cetuximab with chemoradiotherapy in pati...
- Stacey Layman DDS – Pulse Oximetry as a Screening ...
- Contents
- Forthcoming Events
-
▼
Μαρ 01
(406)
- ► Φεβρουαρίου (10753)
- ► Ιανουαρίου (10529)
-
►
2016
(16402)
- ► Δεκεμβρίου (7478)
- ► Φεβρουαρίου (900)
- ► Ιανουαρίου (1250)
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου