<span class="paragraphSection"><div class="boxTitle">Abstract</div>Atrial fibrillation (AF) is a common arrhythmia that poses a significant risk of stroke. Cross-sectional and case-control studies have shown evidence of associations between AF and breast or colorectal cancer, but there have been no longitudinal studies in which this has been assessed. We prospectively examined a cohort of 93,676 postmenopausal women enrolled in the Women's Health Initiative from 1994 to 1998 to determine whether there are relationships between baseline AF and the development of invasive breast or colorectal cancer. The prevalence of self-reported physician diagnosis of AF at baseline was 5.1%. Over approximately 15 years of follow-up, the incidence of invasive breast cancer was 5.7%, and the incidence of colorectal cancer was 1.6%. Adjusted hazard ratios and 95% confidence intervals were obtained using Cox proportional hazards models. We found no significant association between AF and incident colorectal cancer, but we did see a 19% excess risk of invasive breast cancer among those with AF (adjusted hazard ratio (HR) = 1.19, 95% confidence interval (CI): 1.03, 1.38). Additional adjustment for baseline use of cardiac glycosides attenuated the association between AF and invasive breast cancer (HR = 1.01, 95% CI: 0.85, 1.20). Cardiac glycoside use was strongly associated with incident invasive breast cancer (HR = 1.68, 95% CI: 1.33, 2.12) independent of AF and other confounders. Mechanisms of the associations among breast cancer, AF, and cardiac glycosides need further investigation.</span>
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Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com
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Τετάρτη 1 Μαρτίου 2017
The Associations of Atrial Fibrillation With the Risks of Incident Invasive Breast and Colorectal Cancer
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- Bean peptides have higher in silico binding affini...
- Genetics of Congenital Adrenal Hyperplasia
- Trace element composition of smolt scales from Atl...
- Sonochemical synthesis and characterization of mic...
- Evaluation of the bioaccessible gastric and intest...
- The off-stoichiometry effect on the optical proper...
- Synthesis, crystal structure, and luminescent prop...
- Synthesis, characterization, spectral, thermal ana...
- High performance and prospective application of xa...
- The Lymphatic Anatomy of the Lower Eyelid and Conj...
- Abstracts
- The genetics of brain function and psychophysiolog...
- Acoustic Behavior of Halobacterium salinarum Gas V...
- Mutation analysis of CTNNB1 gene and the ras pathw...
- Influence of third molars in mandibular fractures....
- Papilla and alveolar crest levels in immediate ver...
- Papillary carcinoma in struma ovarii
- A rare case of spontaneous Cushing disease remissi...
- The mystery of puberty initiation: genetics and ep...
- A modified intraoral and extraoral approach osteot...
- Correction of tuberous breast deformity: a retrosp...
- Engineered microenvironments for synergistic VEGF ...
- Impact of caries and dental fluorosis on oral heal...
- Idiopathic avascular necrosis associated with humo...
- Evaluation of the risk of infection associated wit...
- Idiopathic avascular necrosis associated with humo...
- Evaluation of the risk of infection associated wit...
- Editorial Board
- Instructions for Authors
- 2016 SRS Presidential Address
- Table of Contents
- Art Is Long, Life Is Short: Lessons Learned in the...
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- Report of the 2016 SRS Traveling Fellowship
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- Can Postoperative Radiographs Accurately Identify ...
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- Multicenter, randomized, open-label Phase II study...
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- GABAA receptor subtypes in the mouse brain: Region...
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- Liver radiofrequency ablation as emergency treatme...
- Mass Spectrometry Imaging Can Distinguish on a Pro...
- Nonhealing Ulcerated Nodules in a Sporotrichoid Pa...
- Nonhealing Ulcerated Nodules in a Sporotrichoid Pa...
- Hydroa Vacciniforme-Like T-Cell Lymphoma: A Furthe...
- Intraepithelial Melanoma in the Stomach After Trea...
- Psychische Verfassung und psychosoziale Versorgung...
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- IL Second counts
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- Unusual extramedullary hematopoietic neoplasms in ...
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