Acute Bilateral Renal and Splenic Infarctions Occurring during Chemotherapy for Lung Cancer.

Related Articles

Acute Bilateral Renal and Splenic Infarctions Occurring during Chemotherapy for Lung Cancer.

Intern Med. 2016;55(24):3635-3639

Authors: Koyama N, Tomoda K, Matsuda M, Fujita Y, Yamamoto Y, Hontsu S, Tasaki M, Yoshikawa M, Kimura H

Abstract
We herein report a rare case of acute bilateral renal and splenic infarctions occurring during chemotherapy for lung cancer. A 60-year-old man presented with acute and intensive upper abdominal and back pain during chemotherapy with cisplatin and etoposide for lung cancer. Contrast-enhanced computed tomography (CT) revealed bilateral renal and splenic infarctions. After the administration of unfractionated heparin his pain was relieved with a clearance of the infarctions in the CT findings and a recovery of renal dysfunction. Enhanced coagulation by lung cancer and arterial ischemia by chemotherapy may therefore contribute to the development of these infarctions.

PMID: 27980265 [PubMed - indexed for MEDLINE]

http://ift.tt/2pcFG3s