Urticarial vasculitis and associated disorders

Patients often present to allergists with urticarial eruption symptoms. In many instances, these lesions represent chronic idiopathic or spontaneous urticaria.1 Some of these patients may have a condition referred to as urticarial vasculitis (UV), including its variants normocomplementemic urticarial vasculitis (NUV), hypocomplementemic urticarial vasculitis (HUV), and hypocomplementemic urticarial vasculitis syndrome (HUVS) or Schnitzler syndrome.2,3 There are some features that set this condition apart, and in some instances, the disease may be severe enough to require systemic immunosuppressive therapies.

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