Increased IL-13 expression is independently associated with neo-osteogenesis in chronic rhinosinusitis.

Increased IL-13 expression is independently associated with neo-osteogenesis in chronic rhinosinusitis.

J Allergy Clin Immunol. 2017 Jun 07;:

Authors: Oue S, Ramezanpour M, Paramasivan S, Miljkovic D, Cooksley CM, Bassiouni A, Ou J, Psaltis AJ, Wormald PJ, Vreugde S

Abstract
CAPSULE SUMMARY: Increased expression of IL-13 is independently affected by the neo-osteogenesis state in CRS. IL-13 protein increased osteoblastic bone mineralization in vitro. Our findings indicate that IL-13 may contribute to pathological bone remodelling in recalcitrant CRS.

PMID: 28601687 [PubMed - as supplied by publisher]

http://ift.tt/2rhNlPw