Reduction of early nodules after injection of hyaluronic acid filler

Early, noninflammatory filler nodules (those that appear within 1 week after injection) are isolated in such a way that they do not diffuse into surrounding tissue even with massage. The formation of nodules can result in an undesirable cosmetic appearance and can cause discomfort.1 Nodules rarely form when applying proper injection techniques; however, the risk still exists even with experienced physicians.

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