Turning the tide: Clinical utility of PD-L1 expression in squamous cell carcinoma of the head and neck

Squamous cell carcinoma of the head and neck (SCCHN) groups a number of tumours arising from distinct locations in the upper aerodigestive tractus, including nasal and oral cavity, pharynx and larynx [1]. Its association with tobacco and alcohol has been investigated and confirmed in various trials [2,3]. Moreover a number of cases of SCCHN, in particular tumours arising from the oropharynx, are linked to human papillomavirus (HPV) infection [4–6].

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