A new case of Giant Cell ‘Reparative’ Granuloma of the temporal bone related to trauma

Publication date: Available online 12 July 2017
Source:Interdisciplinary Neurosurgery
Author(s): Adinda De Pauw, Sophie Lunskens, Bob D'haen, An Vonck, Romaric Croes, Kevin Wetzels, Bart Van Zieleghem
Giant Cell Reparative Granuloma (GCRG) is an uncommon benign non-neoplastic lesion that most commonly affects the mandible and maxilla.Only sporadic cases involving the skull base have been reported.The etiology of GCRG is uncertain but may be related to trauma.The origin of 'reparative' in the name comes from these lesions appearing after bone trauma.We present a new case of GCRG in the temporal bone of possible posttraumatic origin.To distinguish this type of lesions from true giant cell tumours of bone, from brown tumours, from inflammatory lesions or metastatic lesions, histologic examination is required.The true giant cell tumours of bone are the most important to diagnose as these are generally considered to have a prognosis that is worse than GCRG and require adjunctive radiotherapy in addition to surgical excision.



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