Plasticity of immune system vs. memory therapy IST

Publication date: Available online 23 May 2017
Source:Allergologia et Immunopathologia
Author(s): A. Tammaro, I. Romano, F. Persechino, F.R. Parisella, I. Trimarchi, S. Persechino
BackgroundPharmacotherapy and immunotherapy are the main treatments for allergic diseases to inhalants.ObjectiveThis study investigates whether to repeat short cycles of immunotherapy after 3 or 5 years the from interruption of the first therapeutic cycle, lasting 3–4 years, to maintain immune memory in individuals subjected to IST.Methods and ResultsWe have compared two groups, one of 452 patients who, after the first treatment for 3–4 years of IST, performed a cycle of four months after three and 10 years from the suspension, and a second group of 126 individuals who have performed only the IST treatment for 3–4 years. The best results were obtained in the first group.ConclusionsThese results are due to the immune system's plasticity, a very important concept in clinical practice.



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