P299 Plasma cell dyscrasia in primary selective IgM deficiency

There is an increased prevalence of autoimmunity and malignancies; however, no cases of plasma cell dycrasia have been described in selective IgM deficiency (SIGMD). We present two cases of SIGMD, one with multiple myeloma and secondary amyloidosis of the GI tract; and the second with IgAλ monoclonal gammopathy of undetermined significance (MGUS).

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