Publication date: November 2017
Source:Journal of Dairy Science, Volume 100, Issue 11
Author(s): Anthony K. McNeel, Brenda C. Reiter, Dan Weigel, Jason Osterstock, Fernando A. Di Croce
The objective of this study was to evaluate the efficacy of wellness trait genetic predictions in commercial herds of US Holstein cows from herds that do not contribute phenotypic information to the evaluation. Tissue samples for DNA extraction were collected from more than 3,400 randomly selected pregnant Holstein females in 11 herds and 2 age groups (69% nulliparous, 31% primiparous) approximately 30 to 60 d before their expected calving date. Lactation records from cows that calved between September 1, 2015, and December 31, 2015, were included in the analysis. Genomically enhanced predicted transmitting abilities for the wellness traits of retained placenta, metritis, ketosis, displaced abomasum, mastitis, and lameness were estimated by the Zoetis genetic evaluation and converted into standardized transmitting abilities. Mean reliabilities of the animals in the study ranged between 45 and 47% for each of the 6 traits. Animals were ranked by their standardized transmitting abilities within herd and age group then assigned to 1 of 4 groups of percentile-based genetic groups of equal size. Adverse health events, including retained placenta, metritis, ketosis, displaced abomasum, mastitis, and lameness, were collected from on-farm herd management software, and animal phenotype was coded as either healthy (0), diseased (1), or excluded for each of the 6 outcomes of interest. Statistical analysis was performed using a generalized linear mixed model with genetic group, age group, and lactation as fixed effects, whereas herd and animal nested within herd were set as random effects. Results of the analysis indicated that the wellness trait predictions were associated with differences in phenotypic disease incidence between the worst and best genetic groups. The difference between the worst and best genetic groups in recorded disease incidence was 2.9% for retained placenta, 10.8% for metritis, 1.1% for displaced abomasum, 1.7% for ketosis, 7.4% for mastitis, and 3.9% for lameness. Odds ratio estimates between the highest and lowest genetic groups ranged from 1.6 (lameness) to 17.1 (displaced abomasum) for the 6 traits analyzed. These results indicate that wellness trait information of young calves and heifers can be used to effectively predict meaningful differences in future health performance. Improving wellness traits through direct genetic selection presents a compelling opportunity for dairy producers to help reduce disease incidence and improve profitability when coupled with sound management practices.
http://ift.tt/2xyBVoK
Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com
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! # Ola via Alexandros G.Sfakianakis on Inoreader
Η λίστα ιστολογίων μου
Τετάρτη 11 Οκτωβρίου 2017
Validation of genomic predictions for wellness traits in US Holstein cows
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- Microphthalmia with linear skin defects (MLS) synd...
- Linear IgA bullous dermatosis associated with amyo...
- Milia: a useful clinical marker of CYLD mutation c...
- Microphthalmia with linear skin defects (MLS) synd...
- Linear IgA bullous dermatosis associated with amyo...
- Milia: a useful clinical marker of CYLD mutation c...
- Scorpion bite-induced ischaemic stroke
- Oesophageal ischaemia: an uncommon cause of chest ...
- Posterior fossa progressive multifocal leukoenceph...
- Subclinical meningoventriculitis as a cause of obs...
- A unique case of nephrogenic systemic fibrosis fro...
- Allergic bronchopulmonary mycosis presenting as a ...
- Unusual case of prosthetic joint infection caused ...
- Cryptococcus neoformans osteomyelitis and intramus...
- Olfactory bulb agenesis with normal sexual hormones
- Hydatid cyst of the thigh: a challenging diagnosis
- Syncope from radiation-induced baroreceptor failure
- Live 'Baby dance among the red blood cells
- Erdheim-Chester disease: atypical presentation of ...
- Radioactive and stable cesium isotope distribution...
- Cancer Immunotherapy Trials Underutilize Immune Re...
- A Comprehensive Review of Sequencing and Combinati...
- Cost‐Effectiveness of Nivolumab in Recurrent Metas...
- Outcomes of a Specialized Interdisciplinary Approa...
- Prof. Gian Franco Bottazzo MD FRCP FRCPath (1946–2...
- Luciano Martini (1927–2017): a memoir
- Peritoneal pre-conditioning reduces macrophage mar...
- Synchronous HPV-Related Cancer of Bilateral Tonsil...
- Synchronous HPV-Related Cancer of Bilateral Tonsil...
- Management of Patients who Receive an Organ Transp...
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- Venous Thromboembolism After Adult Lung Transplant...
- The Optimization of the Prevascularization Procedu...
- Interactive effects of PAHs with different rings a...
- In search of a comprehensible set of endpoints for...
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- Prognostic significance of standardized uptake val...
- Fluoride containing bioactive glass composite for ...
- Structural and Ultrastructural Analyses of Bone Re...
- Effect of an alkaline environment on the engineeri...
- Continuous positive airway pressure treatment with...
- The effect of sleep duration and sleep quality on ...
- Assessment of intervention-related changes in non-...
- Prevalence of sleep-disordered breathing in Japane...
- Longitudinal associations between sleep and anxiet...
- Analysis and experimental evaluation of shunt acti...
- Long-term treatment with dopamine D3 receptor agon...
- Gender differences in sleep symptoms after repeat ...
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- The role of α1- and α2-adrenoceptor subtypes in th...
- Audiological findings in a de novo mutation of ANK...
- The addition of PRP to facial lipofilling: a doubl...
- The lateral thigh perforator (LTP) flap for autolo...
- Complications and Patient-Reported Outcomes after ...
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- Tumour auto-contouring on 2d cine MRI for locally ...
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- Parental perceptions of childhood seasonal influen...
- Evaluation of T and B memory cell responses elicit...
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- Investigating the candidacy of a capsular polysacc...
- Cost-effectiveness of a potential group B streptoc...
- Adjuvanting an inactivated influenza vaccine with ...
- Value of an in-depth analysis of unpublished data ...
- Trends in pneumococcal meningitis hospitalizations...
- CHRONOVAC VOYAGEUR: A study of the immune response...
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- EZH2 regulates dental pulp inflammation by direct ...
- A dual energy micro-CT methodology for visualizati...
- Different levels of visual perceptual skills are a...
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- Microarray analysis of subcutaneous adipose tissue...
- Survival Disparity Following Abdominal Aortic Aneu...
- Prevalence of pediatric alopecia areata among 572,...
- A meta-analysis of nevus-associated melanoma: Prev...
- Spectrum of orocutaneous disease associations
- Editorial Board
- CME examination
- Atypical features and systemic associations in ext...
- High prevalence of combination tanning among under...
- Spectrum of orocutaneous disease associations
- Assessment of dermatology clinic resources at safe...
- CME examination
- Intrathyroidal carotid artery and nonrecurring rig...
- Chimeric thoracoacromial artery perforator flap fo...
- Pathologic significance of a novel oncoprotein in ...
- Intrathyroidal carotid artery and nonrecurring rig...
- Familial clustering of oropharyngeal squamous cell...
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